Visceral leishmaniasis: A chronic and potentially fatal parasitic disease of the viscera (particularly the liver, spleen, bone marrow and lymph nodes) due to infection by Leishmania donovani. Also known as Kala-azar.
Leishmania donovani is transmitted by sandfly bites in parts of Asia (primarily India), Africa (primarily Sudan) and South America (primarily Brazil) where all together there are an estimated half million cases per year. There are also several hundred cases yearly in Europe (primarily in the Mediterranean region) and a few in North America.
Visceral leishmaniasis can cause no or few symptoms but typically is associated with fever, loss of appetite (anorexia), fatigue, enlargement of the liver, spleen and nodes and suppression of the bone marrow. Visceral leishmaniasis also increases the risk of other secondary infections. The first oral drug found to be effective for treating visceral leishmaniasis is miltefosine.
The name "Leischmania donovani" honors two men: the British pathologist William Boog Leishman who in 1903 wrote about the protozoa that causes kala-azar and the researcher C. Donovan, who made the same discovery independently the same year.
Library > Science > Sci-Tech Dictionary ( Ã¢â‚¬Â²visÃ‚Â·Ã‰â„¢Ã‚Â·rÃ‰â„¢l Ã¢â‚¬Â²lÃ„â€œshÃ‚Â·mÃ‰â„¢Ã¢â‚¬Â²nÃ„Â«Ã‚Â·Ã‰â„¢Ã‚Â·sÃ‰â„¢s ) ( medicine ) A severe, generalized, and often fatal infection, caused by ...
Leishmaniasis includes two major diseases, cutaneous leishmaniasis and visceral leishmaniasis, caused by more than 20 different leishmanial species.
Information on the disease and iOWH's ongoing work on developing the antibiotic paromomycin as a new cure for visceral leishmaniasis.
Visceral leishmaniasis (VL) or kala-azar is a chronic protozoan infection in humans associated with significant global morbidity and mortality.
Visceral leishmaniasis (VL), also known as kala-azar, black fever, and Dumdum fever,:426 is the most severe form of leishmaniasis. Leishmaniasis is a disease caused by ...