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Definition of «Repair, mismatch»

Repair, mismatch: A system within the cell for correcting errors in DNA that works by detecting and replacing bases in the DNA that are wrongly paired (mismatched bases). The system repairs the mismatch.

When there is a mismatch in the DNA, a mismatch correction enzyme goes to that strand of DNA and removes a segment of the strand containing the mismatched base. The gap in the strand is then filled through the action of the enzyme DNA polymerase.

For More Information «Repair, mismatch»

  • Mismatch Repair - Roswell Park Cancer Institute | Understand ...

    This information was most recently updated November 9, 2006. Excision Repair. The major DNA repair mechanisms take advantage of the facts that DNA is double-stranded and ...

  • DNA Repair Mechanisms - Welcome to Web Books Publishing

    There are three major DNA repairing mechanisms: base excision, nucleotide excision and mismatch repair. Table 7-G-1. Proteins involved in the DNA repairing ...

  • Mismatch Repair

    Molecular Genetics Mismatch Repair Facts | Interpretations | Further Info. | Other Pages. Procaryotes and eucaryotes have evolved similar systems to repair DNA by mismatch repair.

  • DNA Repair

    Nucleotide Excision Repair (NER) Mismatch Repair (MMR) Direct Reversal of Base Damage. Perhaps the most frequent cause of point mutations in humans is the spontaneous addition ...

  • HHMI's BioInteractive - Mismatch Repair - Howard Hughes ...

    More About Mismatch Repair. During DNA replication mistakes can occur as DNA polymerase copies the two strands. The wrong nucleotide can be incorporated into one of the ...