Bumetanide (byoo-MET-uh-nide)Brand Name:
This is a strong "water pill" (diuretic). Using too much of Bumetanide can lead to serious water and mineral loss. Therefore, it is important that you be monitored by your doctor. Promptly notify your doctor if you become very thirsty, have a dry mouth, become confused, or develop muscle cramps/weakness.
Bumetanide are used for:
Treating swelling caused by excess body water associated with heart failure or kidney or liver disease. It may also be used for other conditions as determined by your doctor.
Bumetanide are a loop diuretic. It works by forcing the kidney to eliminate sodium, potassium, and water.
Do NOT use Bumetanide if:
- you are allergic to any ingredient in Bumetanide
- you have no urine formation
- you have kidney disease and a significant decrease in urine formation to less than 16 oz/day (500 mL/day)
- you have severe depletion of blood electrolytes (minerals in the blood [eg, sodium, calcium, potassium, chlorine, magnesium, bicarbonate])
- you have brain and nervous system problems caused by severe liver disease
Contact your doctor or health care provider right away if any of these apply to you.
Before using Bumetanide:
Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have excess fluid in or around your abdomen, hearing problems, high blood levels of nitrogen, diabetes, liver or kidney problems, low urine output, or high levels or uric acid
- if you are dehydrated or have had a heart attack
- if you are allergic to sulfa medicines
- if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, or dizziness) to any other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide
Some MEDICINES MAY INTERACT with Bumetanide. Tell your health care provider if you are taking any of the following medicines.
- Ibuprofen, probenecid, or indomethacin because they may decrease Bumetanide's effectiveness
- Aminoglycosides (eg, gentamicin) because the risk of hearing loss may be increased
- Chloral hydrate, digitalis glycosides, or lithium because their actions and the risk of their side effects may be increased by Bumetanide
This may not be a complete list of all interactions that may occur. Ask your health care provider if Bumetanide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Bumetanide:
Use Bumetanide as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Bumetanide by mouth with or without food.
- Bumetanide may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
- If you miss a dose of Bumetanide, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Bumetanide.
Important safety information:
- Bumetanide may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Bumetanide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Bumetanide may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Bumetanide may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Bumetanide. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Your doctor may have also prescribed a potassium supplement for you. If so, follow the dosing carefully. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor.
- Diabetes patients - Bumetanide may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Lab tests, including kidney function, serum urea nitrogen (BUN), and electrolyte levels, may be performed while you use Bumetanide. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Bumetanide with caution in the ELDERLY; they may be more sensitive to its effects, especially low blood pressure.
- Bumetanide should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bumetanide while you are pregnant. It is not known if Bumetanide are found in breast milk. Do not breast-feed while taking Bumetanide.
Possible side effects of Bumetanide:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Dizziness or lightheadedness when sitting up or standing; drowsiness; headache; low blood pressure.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; diarrhea; excessive urination; extreme thirst or dry mouth; hearing loss; kidney failure; loss of appetite; muscle pain or cramps; nausea; rapid or irregular heartbeat; restlessness; ringing in the ears; unusual tiredness or weakness; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include confusion; dizziness; dry mouth; excessive urination followed by a decrease in amount of urine; loss of appetite; muscle cramps; stomach cramps; weakness; weak or irregular heartbeat.Proper storage of Bumetanide:
Store Bumetanide at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bumetanide out of the reach of children and away from pets.
- If you have any questions about Bumetanide, please talk with your doctor, pharmacist, or other health care provider.
- Bumetanide are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Bumetanide. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Bumetanide Prescribing Information (FDA)
- Bumetanide Professional Patient Advice (Wolters Kluwer)
- Bumetanide Detailed Consumer Information (PDR)
- bumetanide Advanced Consumer (Micromedex) - Includes Dosage Information
- bumetanide Concise Consumer Information (Cerner Multum)
- Bumex Prescribing Information (FDA)