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Drugs reference index «A/T/S»


Brand names: Erythromycin, Topical, A/T/S, Erycette, T-Stat

Why is A/T/S prescribed?

Topical erythromycin (applied directly to the skin) is used for the treatment of acne.

Most important fact about A/T/S

For best results, you should continue the treatment for as long as prescribed, even if your acne begins to clear up. This medicine is not an instant cure.

How should you take A/T/S?

Use exactly as prescribed by your doctor.

Thoroughly wash the affected area with soap and water and pat dry before applying medication.

Moisten the applicator or pad with the medication and lightly spread it over the affected area. A/T/S Topical Gel should not be rubbed in.

  • If you miss a dose...Apply the forgotten dose as soon as you remember. If it is almost time for the next application, skip the one you missed and go back to your regular schedule.
  • Storage instructions...This medicine can be stored at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using topical erythromycin.

  • Side effects may include:Burning sensation, dryness, hives, irritation of the eyes, itching, oiliness, peeling, scaling, tenderness, unusual redness of the skin

Why should A/T/S not be prescribed?

Erythromycin should not be used if you are sensitive to or have ever had an allergic reaction to any of the ingredients.

Special warnings about A/T/S

This type of erythromycin is for external use only. Do not use it in the eyes, nose, or mouth.

If the acne does not improve after 6 to 8 weeks of treatment, or if it gets worse, stop using the topical erythromycin preparation and call your doctor.

The use of antibiotics can stimulate the growth of other bacteria that are resistant to the antibiotic you are taking. If new infections (called superinfections) occur, talk to your doctor. You may need to be treated with a different antibiotic drug.

If you develop diarrhea, let your doctor know right away. Drugs such as erythromycin can cause a potentially serious intestinal inflammation.

The use of other topical acne medications in combination with topical erythromycin may cause irritation, especially with the use of peeling, scaling, or abrasive medications.

The safety and effectiveness of A/T/S and Erycette have not been established in children.

Possible food and drug interactions when taking A/T/S

If topical erythromycin is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining topical erythromycin with other topical acne medications.

Special information if you are pregnant or breastfeeding

The effects of topical erythromycin during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Erythromycin may appear in breast milk and could affect a nursing infant. If A/T/S is essential to your health, your doctor may advise you to stop breastfeeding until your treatment with erythromycin is finished.

Recommended dosage for A/T/S

Apply solution to the affected area 2 times a day. Moisten the applicator or a pad, then spread over the affected area. Use additional pads as needed. Apply gel products as a thin film over the affected area once or twice a day.

Make sure the area is thoroughly washed with soap and water and patted dry before applying medication. Thoroughly wash your hands after application of the medication.

Reducing the frequency of applications may reduce peeling and drying.


Although overdosage is unlikely, any medication used in excess can have serious consequences. If you suspect an overdose, seek medical treatment immediately.

  • A/T/S Concise Consumer Information (Cerner Multum)
  • A/T/S Topical Advanced Consumer (Micromedex) - Includes Dosage Information
  • Akne-Mycin Ointment MedFacts Consumer Leaflet (Wolters Kluwer)
  • Emcin Clear Pad MedFacts Consumer Leaflet (Wolters Kluwer)
  • Emgel Gel MedFacts Consumer Leaflet (Wolters Kluwer)
  • Eryderm Solution MedFacts Consumer Leaflet (Wolters Kluwer)
  • Erygel Prescribing Information (FDA)
  • Erythra-Derm Prescribing Information (FDA)
  • Romycin Advanced Consumer (Micromedex) - Includes Dosage Information
  • Romycin Ointment MedFacts Consumer Leaflet (Wolters Kluwer)
  • Staticin Prescribing Information (FDA)
  • T-Stat Prescribing Information (FDA)