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Drugs reference index «Neptazane»


Generic name: MethazolamideBrand names: Neptazane

Why is Neptazane prescribed?

Neptazane, anhydrase is used to treat the eye condition called chronic open-angle glaucoma. This type of glaucoma is caused by a gradual blockage of the outflow of fluid in the front compartment of the eye over a period of years, causing a slow rise in pressure. It rarely occurs before the age of 40. Neptazane is also used in the type called acute angle-closure glaucoma when pressure within the eye must be lowered before surgery.

Most important fact about Neptazane

This medication is related to sulfa drugs and can cause allergic reactions, including fever, rash, redness and peeling of the skin, hives, difficulty breathing, serious skin and blood disorders, and even death. Make sure your doctor is aware of any drug reactions you have experienced. He or she should monitor your blood while you are taking Neptazane. Call your doctor immediately if you experience any allergic symptoms.

How should you take Neptazane?

Take Neptazane exactly as prescribed. Your doctor may have you use it with other eye medications.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store at room temperature.

Neptazane side effects

Side effects cannot be anticipated. If any occur or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Neptazane. Most reactions to Neptazane have been mild and disappear when the medication is stopped or the dosage is adjusted.

  • Side effects may include:Confusion, depression, diarrhea, dizziness, drowsiness, excessive urination, fatigue, fever, general feeling of not being well, headache, hearing problems, loss of appetite, nausea and vomiting, rash, ringing in the ears, severe allergic reaction, taste changes, temporary nearsightedness, tingling in fingers, toes, hands, or feet

Why should Neptazane not be prescribed?

Neptazane is not for use against all types of glaucoma--only the ones mentioned in "Why is Neptazane prescribed?" Also, you should not use Neptazane if you have kidney or liver disease, adrenal gland disorders, or low sodium or potassium levels.

Special warnings about Neptazane

Neptazane can aggravate acidosis, a condition in which the blood is too acidic.

If you have emphysema or a lung blockage, Neptazane will be prescribed cautiously.

Possible food and drug interactions when taking Neptazane

If Neptazane is taken with certain other drugs, the effects of either could be increased, decreased, or altered.

Neptazane and high-dose aspirin taken at the same time can cause loss of appetite, rapid breathing, lethargy, coma, and even death.

Use of Neptazane with steroids may lower your potassium level.

Special information if you are pregnant or breastfeeding

The effects of Neptazane in pregnancy have not been adequately studied. Neptazane should be used by a pregnant woman only if the potential benefit outweighs the potential risk to the developing baby. If you are pregnant or plan to become pregnant, inform your doctor immediately. Neptazane may appear in breast milk and could affect a nursing infant. If Neptazane is essential to your health, your doctor may advise you to stop breastfeeding until your treatment with Neptazane is finished.

Recommended dosage for Neptazane


The usual dosage is 50 milligrams to 100 milligrams taken 2 to 3 times a day.


Any drug taken in excess can have serious consequences. If you suspect an overdose of Neptazane, seek medical attention immediately.

  • Neptazane Concise Consumer Information (Cerner Multum)
  • Methazolamide Prescribing Information (FDA)
  • Methazolamide Professional Patient Advice (Wolters Kluwer)
  • Methazolamide MedFacts Consumer Leaflet (Wolters Kluwer)