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Drugs reference index «Lyrica»


Generic name: PregabalinBrand names: Lyrica

Why is Lyrica prescribed?

Lyrica is used to treat nerve pain associated with diabetes and the after-effects of shingles (herpes zoster infection). It is also used together with other drugs to treat a form of epilepsy characterized by partial seizures.

Most important fact about Lyrica

Lyrica can cause dizziness, sleepiness, and blurred or double vision. To prevent injury to yourself and others, use caution when driving, operating machinery, or engaging in hazardous activities until you know how the drug affects you.

How should you take Lyrica?

Take Lyrica exactly as your doctor prescribes, with or without food, at about the same time every day. Do not stop taking Lyrica suddenly or change your dose without your doctor's approval. If not tapered slowly over the course of at least a week, discontinuing treatment with Lyrica can cause headaches, nausea, diarrhea, or trouble sleeping.

  • If you miss a dose...Take the forgotten dose as soon as you remember. However, if it is almost time for you next dose, skip the one you missed and return to your regular schedule. Do not take two doses at once.
  • Storage instructions...Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Lyrica.

  • Side effects may include:Blurry vision, dizziness, dry mouth, sleepingess, swelling of hands and feet, trouble concentrating, weight gain

Why should Lyrica not be prescribed?

Do not take Lyrica if you are allergic to any of its ingredients.

Special warnings about Lyrica

Lyrica should be used with caution if you are over 65 years, or if you have kidney disease, heart disease including heart failure, or a bleeding disorder.

Contact your doctor right away if you develop swelling of the hands and feet, muscle pain or weakness, or skin sores.

Men who plan to father a child, or whose female partners have become pregnant, must seek expert medical advice about the risks associated with Lyrica.

Possible food and drug interactions when taking Lyrica

If Lyrica is taken with certain drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Lyrica with any of the following:

AntihistaminesAnxiety medicationDiabetes medication such as pioglitazone or rosiglitazoneNarcotic pain medicationSeizure medicationsSleep medicationsTranquilizers

Drinking alcohol while taking Lyrica can make you dizzy or sleepy and should be avoided.

Special information if you are pregnant or breastfeeding

The effects of taking Lyrica during pregnancy have not been studied. Lyrica taken by a male partner may affect an unborn baby. If you are pregnant or plan to become pregnant, contact your doctor immediately.

It is not known whether Lyrica appears in breast milk; talk to your doctor if you plan to breastfeed.

Recommended dosage for Lyrica


Nerve Pain Due to Diabetic Peripheral NeuropathyThe usual starting dose is 50 milligrams taken three times a day. Depending on your response, the doctor may increase your dose to 100 milligrams three times daily. You may be prescribed a lower dose if you have kidney problems.

Nerve Pain Due to ShinglesThe usual starting dose is 75 to 150 milligrams taken two times a day, or 50 to 100 milligrams taken three times a day. You may be prescribed a lower dose if you have kidney problems.

Epilepsy (partial seizures)The usual starting dose is 50 milligrams taken three times a day, or 75 milligrams taken two times a day. Depending on your response, the doctor may increase the total daily dose up to 600 milligrams a day. You may be prescribed a lower dose if you have kidney problems.


Any medication taken in excess can have serious consequences. If you suspect an overdose, seek emergency treatment immediately.

  • Lyrica Prescribing Information (FDA)
  • Lyrica Consumer Overview
  • Lyrica Advanced Consumer (Micromedex) - Includes Dosage Information
  • Lyrica MedFacts Consumer Leaflet (Wolters Kluwer)
  • Pregabalin Professional Patient Advice (Wolters Kluwer)

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