Trade Names:Buckley's Cough- Liquid 100 mg per 5 mL
Trade Names:Diabetic Tussin EX- Liquid 100 mg per 5 mL
Trade Names:Guiatuss- Syrup 100 mg per 5 mL
Trade Names:Humibid Maximum Strength- Tablets, extended-release 1,200 mg
Trade Names:Liquibid- Tablets 400 mg
Trade Names:Mucinex- Tablets, extended-release 600 mg
Trade Names:Naldecon Senior EX- Liquid 200 mg per 5 mL
Trade Names:Organidin NR- Tablets 200 mg- Liquid 100 mg per 5 mL
Trade Names:Robitussin- Syrup 100 mg per 5 mL
Trade Names:Scot-tussin Expectorant- Syrup 100 mg per 5 mL
Trade Names:Siltussin SA- Syrup 100 mg per 5 mL
Trade Names:Tussin- Syrup 100 mg per 5 mLBalminil Expectorant (Canada)Robitussin Extra Strength (Canada)
May enhance output of respiratory tract fluid by reducing adhesiveness and surface tension, thus facilitating removal of viscous mucus and making nonproductive coughs more productive and less frequent. Efficacy not well documented.
The t ½ is 1 h; renal excretion; major urinary metabolite is β-2-(methoxyphenoxy) lactic acid
Temporary relief of cough associated with respiratory tract infections and related conditions such as sinusitis, pharyngitis, bronchitis, and asthma when these conditions are complicated by tenacious mucus or mucus plugs and congestion; effective for productive as well as nonproductive cough, particularly dry, nonproductive cough that tends to injure mucous membranes of the air passages; helps loosen phlegm and thin bronchial secretions in patients with stable chronic bronchitis.
PO 200 to 400 mg every 4 h (max, 2.4 g/day).Children (6 to younger than 12 yr of age)
PO 100 to 200 mg every 4 h (max, 1.2 g/day).Children (2 to younger than 6 yr of age)
PO 50 to 100 mg every 4 h (max, 600 mg/day).Children (6 mo to younger than 2 yr of age)
PO Individualize dose, 25 to 50 mg every 4 h (max, 300 mg/day).Extended-releaseAdults and children (older than 12 yr of age)
PO 600 mg to 1.2 g every 12 h (max, 2.4 g/day).
None well documented.
Guaifenesin may increase renal Cl for urate, which may lower serum uric acid levels; may produce an increase in urinary 5-hyroxyindoleacetic acid, which may interfere with interpretation of this test for diagnosis of carcinoid syndrome; may falsely elevate vanillymandelic acid in certain serotonin metabolite chemical tests because of color interference.
Category C .
May indicate serious condition. Notify health care provider if cough persists for more than 1 wk, tends to recur, or is accompanied by high fever, rash, or persistent headache.
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