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Drugs reference index «Goserelin»



Generic Name: Goserelin (GOE-se-rel-in)Brand Name: Zoladex

Goserelin is used for:

Treating prostate cancer.

Goserelin is a synthetic analogue of gonadotropin-releasing hormone (GnRH) agonist. It works by decreasing the production of testosterone.

Do NOT use Goserelin if:

  • you are allergic to any ingredient in Goserelin
  • you are pregnant, may become pregnant, or are breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Goserelin :

Some medical conditions may interact with Goserelin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of urinary tract blockage, spine or spinal cord problems, diabetes or high blood sugar, or high blood calcium levels
  • if you have weak bones (eg, osteoporosis) or if a family member has had weak bones
  • if you have a history of alcohol abuse or regular tobacco use
  • if you are taking medicines that can weaken the bones, such as anticonvulsants (eg, phenytoin) or corticosteroids (eg, prednisone)

Some MEDICINES MAY INTERACT with Goserelin . However, no specific interactions with Goserelin are known at this time.

Ask your health care provider if Goserelin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Goserelin :

Use Goserelin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Goserelin is usually given as an injection at your doctor's office, hospital, or clinic.
  • If you miss a dose of Goserelin , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Goserelin .

Important safety information:

  • Goserelin may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Goserelin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Worsening of symptoms may occur during the first few weeks of treatment. Notify your doctor if any new or worsened symptoms occur.
  • Goserelin may cause a loss in bone mineral density. This can lead to thin and/or weak bones. Discuss any questions or concerns with your doctor.
  • Goserelin may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
  • Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Goserelin may interfere with certain lab tests, including certain hormonal diagnostic tests. Be sure your doctor and lab personnel know you are using Goserelin .
  • Lab tests, including bone density tests, prostate-specific antigen (PSA) or testosterone levels, or fasting blood glucose, may be performed while you use Goserelin . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Goserelin with extreme caution in CHILDREN. Safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Goserelin may cause harm to the fetus. Avoid becoming pregnant while taking Goserelin . If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Goserelin while you are pregnant. It is not known if Goserelin is found in breast milk. Do not breast-feed while taking Goserelin . Goserelin is not approved for use in women.

Possible side effects of Goserelin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; breast tenderness; decreased sexual desire or ability; diarrhea; dizziness; enlarged breasts; headache; hot flashes; loss of appetite; nausea; sweating; tiredness or weakness; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; blood in the urine or dark urine; bloody vomit; bone pain; breast pain; chest pain; fever or chills; irregular heartbeat; mood or mental changes (eg, depression); severe or persistent headache or dizziness; shortness of breath; sudden, unusual weight gain; sudden vision changes; swelling of the arms or legs; trouble urinating or inability to urinate; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Goserelin :

Goserelin is usually handled and stored by a health care provider. If you are using Goserelin at home, store Goserelin as directed by your pharmacist or health care provider. Keep Goserelin out of the reach of children and away from pets.

General information:

  • If you have any questions about Goserelin , please talk with your doctor, pharmacist, or other health care provider.
  • Goserelin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Goserelin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • goserelin Subcutaneous Advanced Consumer (Micromedex) - Includes Dosage Information
  • Zoladex Prescribing Information (FDA)
  • Zoladex Detailed Consumer Information (PDR)
  • Zoladex Consumer Overview