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Systemic mastocytosis: A form of mastocytosis characterized by infiltrates of mast cells in the skin, lymph nodes, liver, spleen, gastrointestinal tract, bones, and joints with a predisposition to peptic ulcer due to excess stomach acid (caused by the release of histamine from the mast cells).
Treatment may include antihistamines, drugs to reduce stomach acid, migraine headache drugs for headache, and cromolyn for bowel symptoms.
Systemic mastocytosis, often termed systemic mast cell disease (SMCD), is a heterogeneous clonal disorder of the mast cell and its precursor cells.
Systemic mastocytosis information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.
The Mastocytosis Society: In Search of a Cure for Mast Cell Disease
Mastocytosis is characterized by an excessive number of apparently normal mast cells in the skin and, occasionally, in other organs. Characteristic skin lesions, called ...
When there is evidence of bone marrow or internal organ involvement, the disease is referred to as "systemic mastocytosis". Although the majority of cases ...