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SMAD4/DPC4: See: MADH4.
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Smad4/ DPC4 (deleted in pancreatic carcinoma, locus 4) is a tumor suppressor gene lost at high frequency in cancers of the pancreas and other gastrointestinal organs.
The recently described family of Smad molecules are essential mediators of transforming growth factor beta (TGF-beta) signalling. To date, seven members of this family ...
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Suppression of Tumorigenesis and Induction of p15 ink4b by Smad4/DPC4 in Human Pancreatic Cancer Cells 1