Juvenile myelomonocytic leukemia: Abbreviated JMML. A rare cancer of the myeloid cells in the bone marrow, accounting for less than 1% of all childhood leukemia.
JMML is most common in children under four years of age, especially those with genetic disorders called neurofibromatosis 1 (NF1) and Noonan syndrome. Up to 14% of cases of JMML occur in children with NF1.
Few approaches other than hematopoietic stem cell transplantation have resulted in long-term survival for this disease. JMML was formerly called juvenile chronic myelogenous leukemia (juvenile chronic myeloid leukemia, juvenile CML or JCML).
What is leukemia? Leukemia is blood cancer. It develops in the bone marrowÃ¢â¬âthe soft, spongy center of the long bones that produces the three major blood cells:
The JMML Foundation provides support and information to families and practitioners involved with children affected by Juvenile Myelomonocytic Leukemia.
Juvenile myelomonocytic leukemia information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and ...
Juvenile myelomonocytic leukemia (JMML) is an aggressive childhood myeloproliferative disorder characterized by the overproduction of myelomonocytic cells.
Key Points for This Section: Juvenile myelomonocytic leukemia is a childhood disease in which too many myelocytes and monocytes (immature white blood cells) are made in the ...