Imprinting, genomic: The phenomenon of parent-of-origin gene expression. The expression of a gene depends upon the parent who passed on the gene.
For instance, two different disorders - Prader-Willi syndrome and Angelman syndrome -- are due to deletion of the same part of chromosome 15. When the deletion involves the chromosome 15 that came from the father, the child has Prader-Willi syndrome, but when the deletion involves the chromosome 15 that came from the mother, the child has Angelman syndrome.
Genomic imprinting plays a critical role in fetal growth and development. Imprinting is regulated by DNA methylation and chromatin structure.
An introduction to the concept and field of genomic imprinting; from Geneimprint, the genomic imprinting website.
Learning Resources. Research Resources. The Developmental Biology Journal Club. Developmental Biology Tutorial: Genomic Imprinting C. Cristofre Martin
What Is Imprinting? For most genes, we inherit two working copies -- one from mom and one from dad. But with imprinted genes, we inherit only one working copy.
Genomic imprinting and uniparental disomy are factors that influence how some genetic conditions are inherited. Genomic imprinting. People inherit two copies of ...
Geneimprint, the website for information about genomic imprinting and imprinted genes featuring articles, reviews, meeting videos and abstracts, and genetic databases.