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Familial breast cancer: A number of factors have been identified that increase the risk of breast cancer. One of the strongest of these risk factors is the history of breast cancer in a relative. About15-20% of women with breast cancer have such a family history of the disease, clearly reflecting the participation of inherited (genetic) components in the development of some breast cancers. Dominant breast cancer susceptibility genes, including BRCA1 and BRCA2, appear responsible for about 5% of all breast cancer. See related entries to: Breast cancer susceptibility genes; BRCA1; BRCA2.
Familial breast cancer: A number of factors have been identified that increase the risk of breast cancer. One of the strongest of these risk factors is the history of ...
A US Department of Health and Human Service project providing information on genetic and rare diseases. A comprehensive body of resources on Breast cancer, familial
The summary of the published clinical guideline on Familial breast cancer. It links to the published guidance and key documents.
Breast cancer, familial; Breast carcinoma; Cancer of breast; Malignant neoplasm of breast; malignant tumor of breast; Mammary cancer
A small proportion of breast cancers are due to a heritable predisposition. Recently, two predisposition genes, BRCA1 and BRCA2, have been identified and cloned. The ...