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Definition of «Deficiency, LCHAD»

Deficiency, LCHADDeficiency, LCHAD

Deficiency, LCHAD: Acute fatty liver of pregnancy (AFLP) has been found to be associated in some cases with an abnormality of fatty-acid metabolism. This abnormality is a deficiency of the enzyme long-chain-3-hydroxyacyl-CoA dehydrogenease (LCHAD).

The mother (and father) have 50% of normal LCHAD activity and the fetus has no LCHAD activity.

The metabolic disease in the baby's liver apparently causes the fatty liver disease in the mother. In cases of AFLP due to LCHAD deficiency, there is a 25% (or greater) risk of AFLP in each pregnancy.

For More Information «Deficiency, LCHAD»

  • LCHAD deficiency - Genetics Home Reference

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  • LCHAD: Long-Chain 3 Hydroxyacyl CoA Dehydrogense

    LCHAD: Long-Chain 3 Hydroxyacyl CoA Dehydrogense. LCHAD (Long-chain 3 hyroxyacyl CoA Dehydrogense) deficiency is a genetic syndrome with many similarities to ...

  • LCHAD deficiency - NIH Office of Rare Diseases Research (ORDR)

    A US Department of Health and Human Service project providing information on genetic and rare diseases. A comprehensive body of resources on LCHAD deficiency

  • LCHAD deficiency - Socialstyrelsen

    LCHAD deficiency, also known as Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, is a rare disorder described in the database for rare diseases of the Swedish ...


    Disorder name: Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency Acronym: LCHADD . What is LCHADD? What causes LCHADD? If LCHADD is not treated, what problems occur?