Medical Dictionary Definitions A-Z List
Medical Dictionary Definitions A - Z - «B»:
BASE breast cancer gene
BASE breast cancer gene: A breast cancer gene first reported in 2003 that encodes a protein secreted only by breast
cancer and salivary gland cells. Hence the name, BASE (Breast cancer And Salivary gland Expression). The normal breast makes very little, if any, of the BASE protein whereas
Base excision repair
Base excision repair: A process of DNA repair in which an altered base is excised (removed) by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is then filled in by the sequential action of DNA polymerase and DNA ligase. Abbreviated...
Base in DNA
Base in DNA: A unit of the DNA. There are 4 bases: adenine (A),
guanine (G), thymine (T), and cytosine (C). The sequence of bases (for example, CAG) is
the genetic code. ...
Base of tongue
Base of tongue: The back third of the tongue. In contrast to the anterior tongue, which is the front two-thirds of the tongue. The distinction between the anterior and base of the tongue reflects the fact that they are of different embryological origin. The distinction also matters as regards cancer...
Base pair: Two DNA bases complementary to one another (A and T or
G and C) that join the complementary strands of DNA to form the double helix
characteristic of DNA....
Base sequence: The order of the nucleotide bases -- adenine (A), thymine (T), guanine (G), and cytosine (C) -- in a DNA molecule.
Also the order of the nucleotide bases A, G, U (uracil), and C in an RNA molecule....
Base sequence analysis
Base sequence analysis: A method for determining the
order of nucleotide bases in DNA....
Base, pressor: A pressor base is a substance chemically classified as a base (or amine) that is capable of raising the blood pressure.
"Pressor" refers to causing a rise in blood pressure. The word comes from the French verb "presser" meaning "to exert pressure" or "to squeeze."...
Baseline: 1. Information gathered at the beginning of a study from which variations found in the study are measured.
2. A known value or quantity with which an unknown is compared when measured or assessed.
3. The initial time point in a clinical trial, just before a participant starts to receive ...
Basement membrane: A thin membrane upon which is posed a single layer of cells. The basement membrane is made up of proteins held together by type IV collagen. The epithelial cells are anchored with hemidesmosome to the basement membrane. The end result resembles a layer of tiles attached to a thin ...
Basic Local Alignment Search Tool
Basic Local Alignment Search Tool: Abbreviated BLAST. A computer program that identifies homologous genes in different organisms (such as worms, the fruit fly, mice, and humans). Homologous genes are genes in different species that share similar structures and functions....
Basilar: Located at or near the base of a structure, especially the base of the skull.
For example, a basilar fracture is a break in the bone at the base of the skull and can be life-threatening....
Basilar fracture: A break in bone at the base of the skull. About a half of basilar fractures are caused by bicycle or motor vehicle accidents, about a quarter by falls, and a tenth by recreational activities, particularly by diving accidents. The balance are due to other causes. No matter what caus...
Baskerville effect: A fatal heart attack triggered by extreme psychological stress. The effect is named after Charles Baskerville, a character in the Arthur Conan Doyle story "The Hound of the Baskervilles," who suffers a fatal heart attack due to extreme psychological stress.
The term "Baskervill...
Basophil: A type of leukocyte (white blood cell) with coarse bluish-black granules of uniform size within the cytoplasm and typically a bilobate (two-lobed) nucleus. Basophils are so named because their cytoplasmic granules stain with basic dyes. Basophils normally constitute 0.5 to 3% of the periph...