Commonly used brand name(s):
In the U.S.
Available Dosage Forms:
Therapeutic Class: Heavy Metal Chelator
Deferoxamine is used to remove excess iron from the body. This may be necessary in certain patients with anemia who must receive many blood transfusions. It is also used to treat acute iron poisoning, especially in small children.
Deferoxamine combines with iron in the bloodstream. The combination of iron and deferoxamine is then removed from the body by the kidneys. By removing the excess iron, the medicine lessens damage to various organs and tissues of the body. deferoxamine may be used for other conditions as determined by your doctor.
Deferoxamine is to be administered only by or under the immediate supervision of your doctor.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, deferoxamine is used in certain patients with the following medical condition:
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For deferoxamine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to deferoxamine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Deferoxamine is not used for long-term treatment of children up to 3 years of age. Also, younger patients are more likely to develop hearing and vision problems with the use of deferoxamine in high doses for a long time.
The combination of deferoxamine and vitamin C should be used with caution in older patients, since this combination may be more likely to cause heart problems in these patients than in younger adults.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of deferoxamine. Make sure you tell your doctor if you have any other medical problems, especially:
Deferoxamine may sometimes be given at home to patients who do not need to be in the hospital. If you are receiving deferoxamine at home, make sure you clearly understand and carefully follow your doctor's instructions.
The dose of deferoxamine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of deferoxamine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not refrigerate. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Store the mixed medicine at room temperature for no longer than recommended by your doctor or the manufacturer.
It is important that your doctor check your progress at regular visits to make sure that deferoxamine is working properly and to prevent unwanted effects. Certain blood and urine tests must be done regularly to check for the need for dosage changes.
Deferoxamine may cause some people, especially younger patients, to have hearing and vision problems within a few weeks after they start taking it. If you notice any problems with your vision, such as blurred vision, difficulty in seeing at night, or difficulty in seeing colors, or difficulty with your hearing, check with your doctor as soon as possible . The dose of deferoxamine may need to be adjusted.
Do not take vitamin C unless your doctor has told you to do so.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:More common
Hearing and vision problems are more likely to occur in younger patients taking high doses and on long-term treatment.
Deferoxamine may cause the urine to turn orange-rose in color. This is to be expected while you are using deferoxamine.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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