Severe, even fatal, liver and metabolic problems, such as lactic acidosis, have occurred in patients using Zerit . Fatal lactic acidosis has also occurred when Zerit was used in combination with didanosine and other medicines used to treat HIV during pregnancy. Rare cases of muscle weakness or paralysis have occurred, especially in patients with lactic acidosis. Notify your doctor immediately if you develop dark urine, yellowing of the skin or eyes, abdominal or stomach pain, rapid or difficult breathing, drowsiness, muscle aches, or weakness. When used in combination with certain medicines, pancreatitis (sometimes fatal) has occurred on rare occasions. Notify your doctor immediately if you develop severe stomach or abdominal pain.
Treating HIV infection when used in combination with other medicines.
Zerit is a nucleoside analogue antiviral. It blocks the growth of HIV.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Zerit . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Zerit . Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Zerit may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Zerit as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Zerit .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Changes in body fat; constipation; diarrhea; headache; loss of appetite; nausea; vomiting.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chills; dark urine; fever; lactic acid imbalance (general body discomfort, cold feeling, dizziness, lightheadedness, slow or irregular heartbeat); muscle aches or weakness; numbness, tingling, or pain in hands or feet; rapid breathing; severe or persistent nausea and vomiting; shortness of breath; sore throat; stomach pain; sudden weight loss; symptoms of high blood sugar (eg, increased thirst or urination, confusion, unusual drowsiness); unusual tiredness or weakness; weakness in the arms or legs; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include numbness or tingling in the hands or feet; yellowing of the skin or eyes.Proper storage of Zerit :
Store Zerit at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zerit out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Zerit . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.