Generic name: Omeprazole, Sodium bicarbonateBrand names: Zegerid
Zegerid is used to treat intestinal ulcers (duodenal ulcers), stomach ulcers (gastric ulcers), gastroesophageal reflux disease (GERD), and erosive esophagitis. It contains omeprazole, a proton pump inhibitor, and sodium bicarbonate, an antacid, which alters stomach acid and thus improves the absorption of omeprazole.
Both the capsule and oral suspension forms of Zegerid should always be taken on an empty stomach, with water. Do not substitute any other food or liquid in the place of water.
Zegerid should be taken with water on an empty stomach. Take it at least 1 hour before a meal. Do not use any other liquid than water.
Swallow the capsules whole; do not open the capsule and sprinkle on food. Zegerid oral suspension should be emptied into a small cup with 1-2 tablespoons of water. Stir well and drink. Refill the cup with water and drink the remainder.
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zegerid.
Do not take Zegerid if you are allergic to any of its ingredients.
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zegerid.
Also, talk to your doctor about your complete medical history, especially if you are on a sodium-restricted diet. Zegerid capsules contain 300 milligrams of sodium per dose in the form of sodium bicarbonate. Zegerid oral suspension contains 460 milligrams of sodium per dose in the form of sodium bicarbonate. This should be taken into consideration if you need to be on a sodium-restricted diet. In addition, sodium bicarbonate should not be used by people with metabolic alkalosis or hypocalcemia (low blood levels of calcium).
If Zegerid is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zegerid with the following:
AtazanavirDiazepamOther proton pump inhibitorsPhenytoinTacrolimusWarfarin
The effects of Zegerid during pregnancy and breastfeeding are unknown. Talk with your doctor before taking Zegerid if you are pregnant, plan to become pregnant, or are breastfeeding.
Benign Gastric UlcerThe recommended dosage is 40 milligrams (mg) once daily for 4-8 weeks.
Erosive EsophagitisThe recommended dosage is 20 mg once daily for 4-8 weeks. To maintain healing of erosive esophagitis, the daily dose is 20 mg for as long as the doctor prescribes Zegerid.
Short-Term Treatment of Active Duodenal UlcerThe recommended dosage is 20 mg once daily for 4 weeks.
Symptomatic GERDThe recommended dosage is 20 mg once daily for up to 4 weeks.
Upper Gastrointestinal BleedingThe recommended initial dosage is 40 mg followed by another 40 mg 6-8 hours later, and 40 mg daily thereafter for 14 days.
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.