Generic Name: oxybutynin (oral) (OX i BUE ti nin)Brand Names: Ditropan, Ditropan XL, Urotrol
Oxybutynin reduces muscle spasms of the bladder and urinary tract.
Oxybutynin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination.
Oxybutynin may also be used for other purposes not listed in this medication guide.
Before using oxybutynin, tell your doctor if you have glaucoma, liver or kidney disease, an enlarged prostate, myasthenia gravis, ulcerative colitis, a blockage in your stomach or intestines, or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke.Oxybutynin can cause side effects that may impair your vision or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. There are many other medicines that can interact with oxybutynin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating.
untreated or uncontrolled narrow-angle glaucoma;
a blockage in your digestive tract (stomach or intestines); or
if you are unable to urinate.
If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking oxybutynin, tell your doctor if you have:
an enlarged prostate;
a blockage in your stomach or intestines;
a muscle disorder such as myasthenia gravis; or
a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.Take this medication with a full glass of water.
Oxybutynin may be taken with or without food.Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.
Measure the liquid form of oxybutynin with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Try to take this medication at the same time each day.
If you use the extended-release form of oxybutynin, you may notice what looks like part of a tablet in your stools. The tablet shell is not designed to be absorbed by the body, and may therefore pass into the stools without dissolving. This is a normal side effect of oxybutynin extended-release tablets.Store oxybutynin at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke.
hot, dry skin and extreme thirst;
severe stomach pain or constipation;
pain or burning when you urinate; or
urinating less than usual or not at all.
Less serious side effects may include:
dry eyes, blurred vision;
nausea, mild stomach pain or upset;
dizziness, drowsiness, weakness;
sleep problems; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
The following drugs can interact with oxybutynin. Tell your doctor if you are using any of these:
other bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), tolterodine (Detrol), or solifenacin (Vesicare);
HIV /AIDS medicine such as nelfinavir (Viracept) or ritonavir (Norvir);
an antibiotic such as clarithromycin (Biaxin) or erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin);
an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);
irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine); or
an antidepressant such as amitriptyline (Elavil, Etrafon), fluoxetine (Prozac), fluvoxamine (Luvox), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), and others.
This list is not complete and there are many other drugs that can interact with oxybutynin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.