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Drugs reference index «ticarcillin and clavulanate Intravenous»

ticarcillin and clavulanate Intravenous


ticarcillin and clavulanate (Intravenous route)

tye-kar-SIL-in dye-SOE-dee-um, KLAV-ue-la-nate poe-TAS-ee-um

Commonly used brand name(s):

In the U.S.

  • Timentin
  • Timentin Novaplus

Available Dosage Forms:

  • Powder for Solution
  • Solution

Therapeutic Class: Antibiotic

Pharmacologic Class: Ticarcillin

Uses For ticarcillin and clavulanate

Ticarcillin and clavulanate combination is used to treat bacterial infections in many different parts of the body.

Ticarcillin and clavulanate combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria or preventing their growth. However, ticarcillin and clavulanate will not work for colds, flu, or other virus infections.

ticarcillin and clavulanate is available only with your doctor's prescription.

Before Using ticarcillin and clavulanate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ticarcillin and clavulanate, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ticarcillin and clavulanate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ticarcillin and clavulanate combination in children. However, safety and efficacy have not been established in infants below 3 months of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ticarcillin and clavulanate combination in the elderly. However, elderly patients are more likely to have age-related kidney or heart problems, which may require an adjustment in the dose for patients receiving ticarcillin and clavulanate combination.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of ticarcillin and clavulanate. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bleeding problems or
  • Congestive heart failure or
  • Diarrhea or
  • Heart disease or
  • Hypokalemia (low potassium in the blood)—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of ticarcillin and clavulanate

A nurse or other trained health professional will give you ticarcillin and clavulanate. ticarcillin and clavulanate is given through a needle placed in one of your veins.

Precautions While Using ticarcillin and clavulanate

Your doctor will check your progress closely while you are receiving ticarcillin and clavulanate. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

ticarcillin and clavulanate may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have itching; hives; hoarseness; shortness of breath; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth after you receive ticarcillin and clavulanate.

Ticarcillin and clavulanate combination may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Before you have any medical tests, tell the doctor in charge that you are taking ticarcillin and clavulanate. The results of some tests may be affected by ticarcillin and clavulanate.

Ticarcillin and clavulanate combination may decrease the effects of some oral contraceptives (birth control pills). To avoid an unwanted pregnancy, it is a good idea to use additional contraceptive measures with your pills (e.g. condoms, a diaphragm, or a contraceptive foam or jelly) while using ticarcillin and clavulanate.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

ticarcillin and clavulanate Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare
  • Blood in the urine
  • frequent urination
  • lower abdominal cramping
  • painful urination
Incidence not known
  • Abdominal or stomach cramps, pain, or tenderness
  • black, tarry stools
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • bloating
  • changes in skin color
  • chest pain or discomfort
  • chills
  • clay-colored stools
  • convulsions
  • cough
  • dark urine
  • diarrhea
  • diarrhea, watery and severe, which may also be bloody
  • dizziness
  • fast heartbeat
  • fever
  • general tiredness and weakness
  • headache
  • increased thirst
  • irritability
  • itching
  • joint or muscle pain
  • loss of appetite
  • lower back or side pain
  • muscle twitching
  • nausea or vomiting
  • pain, tenderness, or swelling of the foot or leg
  • pinpoint red spots on the skin
  • rash
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • restlessness
  • seizures
  • shortness of breath
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling or inflammation of the mouth
  • swollen glands
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight loss
  • upper right abdominal pain
  • vomiting of blood
  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • change in taste or bad unusual or unpleasant (after) taste
  • difficulty with moving
  • excess air or gas in the stomach or intestines
  • full feeling
  • heartburn
  • muscle aching, cramping, or stiffness
  • passing gas
  • swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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