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Drugs reference index «telavancin Intravenous»

telavancin Intravenous


telavancin (Intravenous route)

tel-a-VAN-sin

Intravenous routePowder for Solution
  • Fetal Risk:
    • Women of childbearing potential should have a serum pregnancy test prior to administration of telavancin hydrochloride.
    • Avoid use of telavancin hydrochloride during pregnancy unless the potential benefit to the patient outweighs the potential risk to the fetus.
    • Adverse developmental outcomes observed in 3 animal species at clinically relevant doses raise concerns about potential adverse developmental outcomes in humans .

Women of childbearing potential should have a serum pregnancy test prior to administration of telavancin hydrochloride. Avoid use during pregnancy unless the potential benefit outweighs the potential risk to the fetus. Adverse developmental outcomes observed in 3 animal species at clinically relevant doses raise concerns about potential adverse developmental outcomes in humans .

Commonly used brand name(s):

In the U.S.

  • Vibativ

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Antibiotic

Chemical Class: Glycopeptide

Uses For telavancin

Telavancin injection is used alone or together with other medicines to treat serious bacterial skin infections.

Telavancin belongs to the group of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, telavancin will not work for colds, flu, or other virus infections.

telavancin is available only with your doctor's prescription.

Before Using telavancin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For telavancin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to telavancin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of telavancin injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of telavancin injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving telavancin injection.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using telavancin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Bepridil
  • Cisapride
  • Dronedarone
  • Levomethadyl
  • Mesoridazine
  • Pimozide
  • Sparfloxacin
  • Thioridazine

Using telavancin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Arsenic Trioxide
  • Asenapine
  • Astemizole
  • Dofetilide
  • Droperidol
  • Fluconazole
  • Gatifloxacin
  • Halofantrine
  • Haloperidol
  • Ibutilide
  • Iloperidone
  • Lapatinib
  • Levofloxacin
  • Lumefantrine
  • Methadone
  • Moxifloxacin
  • Nilotinib
  • Paliperidone
  • Quinidine
  • Sodium Phosphate
  • Sotalol
  • Sunitinib
  • Telithromycin
  • Terfenadine
  • Tetrabenazine
  • Voriconazole
  • Ziprasidone

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of telavancin. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart rhythm problems (e.g., QT prolongation), or a family history of or
  • Kidney problems—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.

Proper Use of telavancin

A nurse or other trained health professional will give you telavancin. telavancin is given through a needle placed in one of your veins.

telavancin comes with a medication guide. Read and follow the instructions in the guide carefully. Ask your doctor if you have any questions.

Precautions While Using telavancin

It is very important that your doctor check your progress while you receive telavancin to make sure that it is working properly. Blood tests may be needed to check for unwanted effects.

Using telavancin while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.

You must have a negative pregnancy test before you will be given telavancin. If you miss a period while you are using telavancin, tell your doctor right away.

Check with your doctor right away if you have blood in the urine, a change in the frequency of urination or amount of urine, difficulty with breathing, drowsiness, increased thirst, loss of appetite, nausea or vomiting, or swelling of the feet or lower legs. These may be symptoms of a serious kidney problem.

telavancin may cause a rare but serious type of infusion reaction called the "Red-man Syndrome." Tell your doctor right away if you start to have itching, hives, chills or fever, a fast heartbeat, nausea or vomiting, a rash or redness of the face, base of the neck, upper body, back, and arms.

Telavancin injection may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

telavancin can cause changes in the heart rhythm, such as a condition called QT prolongation. It may change the way your heart beats and cause fainting or serious side effects in some patients. Contact your doctor right away if you have any symptoms of heart rhythm problems, such as fast, pounding, or irregular heartbeats.

Before you have any medical tests, tell the medical doctor in charge that you are using telavancin. The results of some tests may be affected by telavancin.

telavancin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common
  • Blood in the urine
  • change in frequency of urination or amount of urine
  • difficulty with breathing
  • drowsiness
  • increased thirst
  • loss of appetite
  • nausea or vomiting
  • swelling of the feet or lower legs
  • weakness
Incidence not known
  • Abdominal or stomach tenderness
  • chills or fever
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • fast heartbeat
  • fever
  • hives
  • itching of the skin
  • nausea or vomiting
  • pain, redness, or soreness at the site of injection
  • rash or redness of the face, base of the neck, upper body, back, and arms
  • severe abdominal or stomach cramps and pain
  • watery and severe diarrhea, which may also be bloody

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Bad, unusual or unpleasant (after) taste
  • change in taste
  • diarrhea
  • dizziness
  • foamy urine
Less common
  • Abdominal or stomach pain
  • decreased appetite
  • dry, red, hot, or irritated skin
  • feeling unusually cold
  • shivering

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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