Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index
Search
EN

Drugs reference index «Tamiflu»

Tamiflu
Tamiflu


Tamiflu

Generic Name: oseltamivir (Oral route)

oh-sel-TAM-i-vir

Commonly used brand name(s):

In the U.S.

  • Tamiflu

Available Dosage Forms:

  • Capsule
  • Powder for Suspension

Therapeutic Class: Antiviral

Pharmacologic Class: Neuraminidase Inhibitor, Influenza A&B Virus

Uses For Tamiflu

Oseltamivir belongs to the family of medicines called antivirals, which are used to treat infections caused by viruses. Oseltamivir is used in the treatment of the infection caused by the flu virus (influenza A and influenza B). Oseltamivir may also be used to prevent and treat swine influenza A.

Oseltamivir may reduce flu symptoms (weakness, headache, fever, cough, runny or stuffy nose, and sore throat) by 1 day. Oseltamivir is also used to prevent influenza infection if you have come into close contact with someone who has the flu.

If you receive the flu vaccine every year, continue to do so. Oseltamivir is not a substitute for your yearly flu shot.

This medicine is available only with your doctor's prescription.

Before Using Tamiflu

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of oseltamivir in children younger than 1 year of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of oseltamivir in the elderly.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart disease or
  • Illnesses caused by viruses other than influenza Type A or B or
  • Liver disease or
  • Lung disease or
  • Serious medical problems that may need admission to a hospital or
  • Weakened immune system—Safety of this medicine for people with these conditions is not established.
  • Hereditary fructose intolerance—Use with caution. The oral suspension contains sorbitol, which can make this condition worse.
  • Kidney disease—Use with caution. The effects may be increased because of slower removal of medicine from the body.

Proper Use of Tamiflu

Talk to your doctor about the possibility of getting a flu shot if you or your child have not had one yet. This medicine comes with a patient information insert. Read this information carefully and talk to your doctor if you have any questions.

For patients taking oseltamivir for the treatment of flu: This medicine works best if taken within 2 days of having flu symptoms (weakness, headache, fever, cough, runny or stuffy nose, and sore throat). This medicine should be taken for 5 days. Continue taking this medicine for the full time of treatment even if you begin to feel better after a few days. This will help clear up your infection completely. If you stop taking this medicine too soon, your symptoms may return.

For patients taking oseltamivir for the prevention of flu after an exposure: The medicine should be taken within 2 days of being exposed to the flu. This medicine should be taken for at least 10 days.

You may be take this medicine with meals or on an empty stomach. Taking oseltamivir with food may lessen the possibility of stomach upset.

For patients taking the oral liquid:

  • This medicine is to be taken only by mouth. Shake it well before using. Use the specially marked dosing dispenser that comes with the medicine to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid. If the measuring device is lost or damaged, contact your pharmacist or doctor to find out the appropriate dose.
  • Do not use the medicine after the expiration date on the label. The medicine may not work properly after that date. If you have any questions about this, check with your pharmacist.

If the oral liquid is not available, you may open the capsules and mix the contents in a bowl with sweetened liquids such as regular or sugar-free chocolate syrup. Ask your doctor or pharmacist if you have any questions.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (capsules and suspension):
    • For treatment of the flu:
      • Adults and teenagers—75 milligrams (mg) two times a day (one in the morning and one in the evening) for 5 days.
      • Children 1 year of age and older—Dose is based on body weight and must be determined by your doctor. It is usually between 30 and 75 mg two times a day for 5 days.
      • Children up to 1 year of age—Use and dose must be determined by your doctor.
    • For prevention of the flu:
      • Adults and teenagers—75 milligrams (mg) once a day for at least 10 days.
      • Children 1 year of age or older—Dose is based on body weight and must be determined by your doctor. It is usually between 30 and 75 mg once a day for 10 days.
      • Children up to 1 year of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss a dose or forget to use it, take it as soon as you can except if it is less than 2 hours before your next dose. Take your next dose at the normal time. Do not use extra medicine to make up for a missed dose.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the capsules at room temperature, away from heat, moisture, and direct light.

Store the oral liquid in the refrigerator, away from heat and direct light. Do not freeze. Use the medicine within 10 days after you fill the prescription.

Precautions While Using Tamiflu

It is very important that your doctor check your progress after treatment. This is to make sure that the infection is cleared up completely, and to allow your doctor to check for any unwanted effects.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are using this medicine.

Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin; red skin lesions; severe acne or skin rash; sores or ulcers on the skin; or fever or chills while you are using this medicine.

Oseltamivir may cause some people, especially children and teenagers, to be agitated, irritable, or display other abnormal behaviors, which may result in injury. If you, your child, or your caregiver notice any of these side effects, tell your doctor or your child's doctor right away.

Make sure your doctor knows if you or your child plan to get the live nasal mist flu vaccine before you start using this medicine. You should not receive the vaccine within two weeks before or 48 hours after using this medicine.

If your symptoms do not improve after you finish taking the medicine, or if they become worse, check with your doctor.

Tamiflu Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common
  • Phlegm-producing cough
  • wheezing
Rare
  • Abdominal or stomach cramps or tenderness
  • arm, back, or jaw pain
  • bloating
  • chest pain or discomfort
  • chest tightness or heaviness
  • diarrhea, watery and severe, which may also be bloody
  • drooling
  • facial swelling
  • fast or irregular heartbeat
  • fever
  • hoarseness
  • humerus fracture (broken forearm)
  • increased thirst
  • pain
  • shortness of breath
  • tender glands of the jaw and throat
  • unusual tiredness or weakness
  • unusual weight loss
Incidence not known
  • Blistering, peeling, or loosening of the skin
  • chills
  • convulsions (seizures)
  • dark urine
  • difficulty with swallowing
  • fainting
  • fast, slow, or irregular heartbeat
  • general tiredness and weakness
  • hives or welts
  • itching
  • itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
  • joint or muscle pain
  • light-colored stools
  • loss of bladder control
  • loss of consciousness
  • muscle spasm or jerking of all extremities
  • red skin
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • shortness of breath
  • skin rash
  • skin rash or itching over the entire body
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • sudden loss of consciousness
  • sweating
  • swelling of the face or tongue
  • upper right abdominal pain
  • weakness
  • yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Diarrhea
  • nausea
  • vomiting
Less common
  • Abdominal or stomach pain
  • bloody nose or unexplained nosebleeds (occurs mainly in children)
  • burning, dry, or itching eyes (mainly in children)
  • cough
  • dizziness
  • ear disorder (occurs mainly in children)
  • excessive tearing of the eyes (mainly in children)
  • headache
  • redness, pain, or swelling of the eye or eyelid (mainly in children)
  • trouble with sleeping
Rare
  • Pale skin
  • sneezing
  • troubled breathing
  • troubled breathing with exertion
  • unusual bleeding or bruising
Incidence not known
  • Blistering, crusting, irritation, itching, or reddening of the skin
  • blurred vision
  • cracked, dry, or scaly skin
  • dry mouth
  • flushed, dry skin
  • fruit-like breath odor
  • increased hunger
  • increased urination
  • mood or mental changes
  • skin rash that is encrusted, scaly, and oozing
  • stomachache
  • unexplained weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

  • Tamiflu Prescribing Information (FDA)
  • Tamiflu Detailed Consumer Information (PDR)
  • Tamiflu MedFacts Consumer Leaflet (Wolters Kluwer)
  • Tamiflu Consumer Overview

See Also...