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Drugs reference index «Sutent»



Generic Name: Sunitinib (soo-NI-ti-nib)Brand Name: Sutent

Sutent is used for:

Treating certain types of stomach or intestinal tumors in certain patients. It is also used to treat certain types of kidney cancer. It may also be used for other conditions as determined by your doctor.

Sutent is a multikinase inhibitor. It works by blocking certain enzymes in the body that may be involved in the growth and spread of cancer cells. This helps to slow tumor growth and may decrease the ability of the cancer to spread to other areas of the body.

Do NOT use Sutent if:

  • you are allergic to any ingredient in Sutent
  • you are taking bevacizumab or St. John's wort

Contact your doctor or health care provider right away if any of these apply to you.

Before using Sutent :

Some medical conditions may interact with Sutent . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of kidney function problems, liver problems, or muscle problems
  • if you have a history of congestive heart failure, angina, irregular heartbeat (eg, QT prolongation), slow heartbeat, or other heart problems; recent heart attack or stroke; a blood clot in the lung; blood vessel disease; or if you are at risk for heart problems
  • if you have bleeding problems, high blood pressure, electrolyte problems, adrenal gland problems, thyroid problems, or a seizure disorder (eg, epilepsy)
  • if you have a severe infection, have recently been injured, or will be having surgery

Some MEDICINES MAY INTERACT with Sutent . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antiarrhythmics (eg, amiodarone, quinidine) because serious irregular heartbeat may occur
  • Bevacizumab because a certain type of severe anemia (eg, hemolytic anemia) may occur
  • Clarithromycin, HIV protease inhibitors (eg, indinavir, ritonavir), imidazole antifungals (eg, ketoconazole), nefazodone, telithromycin, or voriconazole because they may increase the risk of Sutent 's side effects
  • Barbiturates (eg, phenobarbital), carbamazepine, dexamethasone, hydantoins (eg, phenytoin), rifabutin, rifampin, rifapentin, or St. John's wort because they may decrease Sutent 's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sutent may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Sutent :

Use Sutent as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Sutent . Talk to your pharmacist if you have questions about this information.
  • Take Sutent by mouth with or without food.
  • Do not open before swallowing.
  • Do not eat grapefruit or drink grapefruit juice while you use Sutent .
  • If you miss a dose of Sutent , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sutent .

Important safety information:

  • Sutent may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Sutent with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Sutent may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • Sutent may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
  • Tell your doctor or dentist that you take Sutent before you receive any medical or dental care, emergency care, or surgery.
  • Skin or hair discoloration may occur while you are using Sutent . Contact your doctor with any questions or concerns.
  • Lab tests, including complete blood cell counts, blood electrolytes, blood pressure checks, thyroid function, urine tests, electrocardiograms (ECG), and other heart function tests, may be performed while you use Sutent . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Sutent should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Sutent may cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sutent while you are pregnant. It is not known if Sutent is found in breast milk. Do not breast-feed while taking Sutent .

Possible side effects of Sutent :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Changes in taste; constipation; decreased appetite; diarrhea; dry, thick, or cracked skin; headache; indigestion; mouth pain or irritation; nausea; nosebleed; skin or hair discoloration; stomach pain or upset; tiredness; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; blistering or rash on the palms of hands and soles of feet; calf swelling or tenderness; chest pain; dark urine; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; mental or mood changes (eg, confusion, decreased alertness, depression, irritability, nervousness); muscle pain, tenderness, or weakness; numbness of an arm or leg; numbness or tingling of the hands or feet; pale stools; seizures; severe or persistent headache, dizziness, stomach pain, back pain, tiredness, or weakness; shortness of breath; swelling of the hands or legs; symptoms of thyroid problems (eg, changes in menstrual period, excessive sweating, increased appetite, increased sensitivity to hot or cold conditions, sudden weight changes, tremors, trouble sleeping); unusual or severe bruising or bleeding (eg, bleeding gums, nosebleeds); vision changes or vision loss; vomit that looks like coffee grounds; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include decreased activity; eye discharge; goose bumps; head shakes; loss of coordination; stomach pain.

Proper storage of Sutent :

Store Sutent at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Sutent out of the reach of children and away from pets.

General information:

  • If you have any questions about Sutent , please talk with your doctor, pharmacist, or other health care provider.
  • Sutent is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Sutent . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Sutent Prescribing Information (FDA)
  • Sutent Concise Consumer Information (Cerner Multum)
  • Sutent Advanced Consumer (Micromedex) - Includes Dosage Information

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