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Drugs reference index «solifenacin»

solifenacin (Oral route)

soe-li-FEN-a-sin

Commonly used brand name(s):

In the U.S.

  • Vesicare

Available Dosage Forms:

  • Tablet

Therapeutic Class: Urinary Antispasmodic

Pharmacologic Class: Antimuscarinic

Uses For solifenacin

Solifenacin is used to treat bladder problems such as frequent need to urinate or loss of control of urinary function.

solifenacin is available only with your doctor's prescription.

Before Using solifenacin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For solifenacin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to solifenacin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on solifenacin have been done only in adult patients, and there is no specific information comparing use of solifenacin in children with use in other age groups.

Geriatric

solifenacin has been tested and has not been shown to cause different side effects or problems in older people than is does in younger adults. However, elderly patients are more likely to be sensitive to anticholinergic agents and may require a lower dose.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using solifenacin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Potassium Chloride

Using solifenacin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Ketoconazole

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of solifenacin. Make sure you tell your doctor if you have any other medical problems, especially:

  • Glaucoma or
  • Stomach problems or
  • Urinary retention—Solifenacin may make these conditions worse.
  • Kidney problems or
  • Liver problems—A lower dose of solifenacin may be necessary.
  • QT prolongation—Solifenacin may make this condition worse.

Proper Use of solifenacin

Dosing

The dose of solifenacin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of solifenacin. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • To treat bladder problems:
      • Adults—5 to 10 milligrams (mg) once a day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of solifenacin, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using solifenacin

solifenacin may cause some people to have vision problems. Make sure your vision is clear before you drive or do anything else that could be dangerous if you are not able to see well.

Use caution during exercise or hot weather. Overheating may result in heat exhaustion.

solifenacin may cause constipation, call your doctor if you get severe stomach pain or become constipated for 3 or more days.

solifenacin may cause dryness of the mouth. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.

solifenacin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Symptoms of Overdose

Get emergency help immediately if any of the following symptoms of overdose occur:

  • Blurred vision
  • confusion
  • constipation
  • delirium or hallucinations
  • difficult urination
  • dizziness
  • drowsiness
  • dry eyes, mouth, nose, or throat
  • dry skin
  • eye pain
  • failure of heel-to-toe exam
  • fast heartbeat
  • fixed and dilated pupils
  • flushing or redness of face
  • nausea
  • tremors
  • troubled breathing
  • vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common
  • Difficulty having a bowel movement (stool)
  • dry mouth
Less common
  • Acid or sour stomach
  • belching
  • bladder pain
  • bloody or cloudy urine
  • blurred vision
  • body aches or pain
  • chills
  • congestion
  • cough
  • decrease in frequency of urination
  • decrease in urine volume
  • diarrhea
  • difficulty in passing urine
  • difficult, burning, or painful urination
  • discouragement
  • dizziness
  • [dribbling] painful urination
  • dry eyes
  • dryness or soreness of throat
  • feeling sad or empty
  • fever
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • headache
  • heartburn
  • hoarseness
  • indigestion
  • irritability
  • joint pain
  • lack of appetite
  • loss of interest or pleasure;
  • lower back or side pain
  • muscle aches and pains
  • nausea
  • nervousness
  • pounding in the ears
  • runny nose
  • shivering
  • slow or fast heartbeat
  • sore throat
  • stomach discomfort upset or pain
  • sweating
  • swelling of the legs
  • tender, swollen glands in neck
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • trouble in swallowing
  • unusual tiredness or weakness
  • upper stomach pain
  • voice changes
  • vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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  • Solifenacin MedFacts Consumer Leaflet (Wolters Kluwer)
  • VESIcare Prescribing Information (FDA)
  • VESIcare Detailed Consumer Information (PDR)
  • Vesicare Consumer Overview

See Also...