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Drugs reference index «Solagé»


Generic name: Mequinol 2%, Tretinoin 0.01%Brand names: Solagé

Why is Solagé prescribed?

Solagé (pronounced "so-la-JAY") is used for removing or lightening age spots, or dark spots that appear on the skin after chronic exposure to the sun. Solagé has only been tested in Caucasians. It is only to be used in combination with sun avoidance or use of protective clothing. Solagé does not cure age spots, and in clinical trials, many patients had their spots darken again after they discontinued treatment.

Most important fact about Solagé

Solagé is a prescription medication. It should only be used under supervision of your doctor as part of a sun avoidance program. This program should also include wearing protective clothing in direct sunlight and avoiding sunlamps.

How should you take Solagé?

Apply Solagé to the age spots using the applicator provided with the medication. Avoid application of Solagé to the surrounding, normally colored skin. Only apply enough Solagé to make the lesion appear moist; do not let the medication drip onto surrounding skin. Do not use Solagé around your eyes, lips, creases of the nose or mucous membranes. If the product gets in your eyes, rinse thoroughly with water and contact your doctor.

You should not shower or bathe the treatment areas for at least 6 hours after application of Solagé. Also, you should wait at least 30 minutes before applying cosmetics.

  • If you miss a dose...Do not try to "make it up." Return to your normal application schedule as soon as you can.
  • Storage instructions...Store at room temperature. Protect from light by returning the bottle to the carton after each use. Keep away from heat or open flame.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Solagé.

  • Side effects may include:Burning, stinging, tingling feeling; dryness; hypopigmentation (the age spot or the skin immediately surrounding it becomes paler than the rest of your skin); irritation; itching; peeling

Why should Solagé not be prescribed?

You should not use Solagé if you are pregnant, attempting to become pregnant, or at a high risk of pregnancy. If you are breastfeeding, you should not use Solagé unless advised otherwise by your doctor.

Do not use Solagé if you have had an allergic reaction to any of its ingredients. Solagé should not be used on children. Do not use Solagé if you have eczema. You should not use Solagé if your skin is particularly sensitive to sunlight or you are taking any medications that have a photosensitizing effect (see "Possible food and drug interactions").

Special warnings about Solagé

It may take up to six months for the full benefits of treatment to be seen. Solagé has not been tested for treatment periods longer than six months. The age spots may return to their original color following discontinuation of Solagé.

Solagé increases the skin's sensitivity to sunlight, and it must be used together with a sun avoidance program. You need to avoid the sun as much as possible and wear protective clothing when in sunlight. Do not use sunlamps. If your skin is sunburned, discontinue treatment until the sunburn has completely healed. Let your doctor know if you are taking any other medications that increase your sensitivity to sunlight (see "Possible food and drug interactions") or if you have an occupation that requires prolonged sun exposure. If you are taking any prescription medicines, non-prescription medicines, or using any facial or skin creams, check with your doctor to make sure they do not interact with Solagé.

Stop treating any age spots that become the same color or lighter than your normally colored skin. If the skin surrounding an age spot becomes lighter than your normally colored skin, stop treating that age spot and contact your doctor. Stop treatment if an age spot becomes darker with treatment.

If you, or a family member, have a history of vitiligo (a skin condition consisting of white patches on various parts of the body), consult your doctor before using Solagé.

Solagé has only been tested in Caucasians and its effect and safety in people with moderately or darkly pigmented skin is not well understood.

Possible food and drug interactions when taking Solagé

Solagé can cause skin dryness. You should be cautious about using any other skin care products that have a drying effect on the skin (products with high concentrations of alcohol, astringents, spices or lime, medicated soaps, or shampoos, permanent wave solutions, electrolysis, hair removal products or waxes, or other preparations or processes that may dry or irritate your skin). If you are using any of these types of products, tell your doctor before using Solagé.

Solagé makes the skin more sensitive to natural and artificial sunlight. Tell your doctor if you are taking any other medications that make your skin more sensitive to sunlight. These include thiazide diuretics, phenothiazines (certain types of antipsychotic medication), and several types of antibiotics (such as tetracyclines, fluoroquinolones, and sulfonamides).

Special information if you are pregnant or breastfeeding

Solagé should not be used if you are pregnant, attempting to become pregnant, or at a high risk of pregnancy. Consult your doctor for adequate birth control measures if you are a female of childbearing potential.

It is not known if Solagé is passed to infants through breast milk. Do not use Solagé if you intend to breast feed, unless advised otherwise by your doctor.

Recommended dosage for Solagé

Use twice daily, at least 8 hours apart.


Applications of larger amounts of Solagé, or more frequent applications than recommended, will not lead to more rapid or better results, and marked redness, peeling, irritation or hypopigmentation may occur. If you accidently injest Solagé, seek emergency treatment immediately.