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Drugs reference index «Sodium Sulfacetamide/Sulfur»

Sodium Sulfacetamide/Sulfur
Sodium Sulfacetamide/Sulfur


Sodium Sulfacetamide / Sulfur

Pronunciation: (SOE-dee-um SUL-fa-SEET-a-mide/SUL-fer)Class: Keratolytic agent

Trade Names:Avar- Cleanser sodium sulfacetamide 10% and sulfur 5%- Gel sodium sulfacetamide 10% and sulfur 5%

Trade Names:Avar-e Emollient- Cream sodium sulfacetamide 10% and sulfur 5%

Trade Names:Avar-e Green- Cream sodium sulfacetamide 10% and sulfur 5%

Trade Names:BP Cleansing Wash- Soap sodium sulfacetamide 10% and sulfur 4%

Trade Names:Clarifoam EF- Foam sodium sulfacetamide 10% and sulfur 5%

Trade Names:Claris- Wash sodium sulfacetamide 10% and sulfur 1%

Trade Names:Clenia- Cream sodium sulfacetamide 10% and sulfur 5%- Foam sodium sulfacetamide 10% and sulfur 5%

Trade Names:Plexion- Soap sodium sulfacetamide 10% and sulfur 5%

Trade Names:Plexion Cleansing Cloths- Pads sodium sulfacetamide 10% and sulfur 5%

Trade Names:Plexion SCT- Cream sodium sulfacetamide 10% and sulfur 5%

Trade Names:Plexion TS- Topical suspension sodium sulfacetamide 10% and sulfur 5%

Trade Names:Roasanil- Soap sodium sulfacetamide 10% and sulfur 5%

Trade Names:Rosac- Cream with sunscreens sodium sulfacetamide 10% and sulfur 5%- Wash sodium sulfacetamide 10% and sulfur 1%

Trade Names:Rosaderm- Cleanser sodium sulfacetamide 10% and sulfur 5%

Trade Names:Rosula- Gel sodium sulfacetamide 10% and sulfur 5%- Cleanser sodium sulfacetamide 10% and sulfur 5%

Trade Names:Rosula Clarifying- Wash sodium sulfacetamide 10% and sulfur 4%

Trade Names:Sumaxin- Pads sodium sulfacetamide 10% and sulfur 4%

Trade Names:Zetacet- Wash sodium sulfacetamide 10% and sulfur 5%

Pharmacology

Sulfacetamide

Competitively antagonizes PABA, an essential component of folic acid synthesis.

Sulfur

Inhibits the growth of Propionibacterium acnes and the formation of free fatty acids.

Indications and Usage

Topical control of acne vulgaris, acne rosacea, and seborrheic dermatitis.

Contraindications

Kidney disease; known hypersensitivity to sulfonamides, sulfur, or any component of the product.

Dosage and Administration

Adults and Children 12 yr of age and older

Topical

Avar cleanser, BP cleansing wash, Claris wash, Clenia foaming wash, Plexion cleanser, Rosac wash, Rosaderm cleanser, Rosanil cleanser, Rosula cleanser, Rosula wash, Zetacet wash

Wet skin and liberally apply to area(s) to be cleansed once or twice daily, massage gently into skin for 10 to 20 seconds working into a full lather, rinse thoroughly and pat dry.

Avar-e Emollient cream, Avar gel, Plexion TS , Rosac cream with sunscreens, Rosula gel

Apply a thin layer to affected area(s) 1 to 3 times daily.

Avar-e Green cream

Apply a thin layer to affected area(s) 1 to 3 times daily. Massage completely and uniformly into the skin.

Clenia emollient cream

Apply thin layer to affected area(s) 1 to 3 times daily. To minimize potential dryness, start with 1 application daily, then gradually increase to 2 to 3 times daily as needed.

Plexion cleansing cloth, Sumaxin cleansing pads

Wash affected area(s) with cleansing cloth or pad once or twice daily. Wet area(s) with water. Wet cloth or pad with a small amount of water and work into a full lather. Cleanse area(s) for 10 to 20 seconds. Rinse thoroughly and pat dry.

Plexion SCT

Wet skin. Apply in a film to entire face, avoiding contact with eyes or mucous membranes. Wait 10 minutes or until dry. Rinse thoroughly with water and pat dry.

General Advice

  • If drying occurs with topical cleanser or wash, it may be controlled by rinsing product off sooner or using less often.

Storage/Stability

Store at controlled room temperature (59° to 86°F). Keep bottle tightly closed.

Avar-e cream, Avar gel, Rosula wash

Store at 59° to 77°F. Do not freeze.

Avar-e Emollient cream, Avar-e Green cream, BP Cleansing Wash

Store at 59° to 86°F. Do not freeze.

Avar cleanser and gel, Clenia emollient cream, Clenia foaming wash, Rosula cleanser and gel, Plexion cleanser, Plexion cleansing cloths, Plexion SCT , Plexion TS , Sumaxin pads

Store at 59° to 77°F.

Claris wash, Rosac cream and wash, Rosaderm cleanser, Zetacet wash

Store at 59° to 86°F.

Rosanil cleanser

Store at 68° to 77°F.

Drug Interactions

None well documented.

Laboratory Test Interactions

None well documented.

Adverse Reactions

Dermatologic

Dryness; erythema; local irritation; itching.

Miscellaneous

Allergic hypersensitivity.

Precautions

Pregnancy

Category C .

Lactation

Undetermined; however, small amounts of orally administered sulfonamides are secreted in breast milk.

Children

Safety and efficacy not determined in children younger than 12 yr of age.

Irritation

If irritation develops, discontinue use and institute appropriate therapy.

Sensitivity

May occur; use caution and careful supervision when prescribing this drug for patients who may be prone to hypersensitivity to topical sulfonamides.

Sodium metabisulfite

May contain sodium metabisulfite, which can cause allergic-type reactions, including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in susceptible individuals.

Patient Information

  • Review prescribed dosing schedule with patient or caregiver.
  • Remind patient or caregiver that product is not to be used in the eye, ear, or mucous membranes.
  • Teach patient or caregiver proper technique for applying product: wash hands; shake lotion and suspension well, then apply thin film to affected area(s) using fingers. Wash hands after applying product.
  • Advise patient or caregiver to contact health care provider if local redness or swelling develops or if skin lesions do not improve or they worsen.

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