Generic name: Clomiphene citrateBrand names: Serophene
Serophene is typically considered a beginning therapy for patients experiencing ovulatory failure or dysfunction. Serophene works by stimulating the body to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH), the hormones necessary for ovulation to occur.
As with other fertility medications, the use of Serophene is associated with multiple births (e.g., twins, triplets). Do not use Serophene if you are already pregnant, as it may cause severe birth defects in your child, such as heart problems, Down syndrome, club foot, cleft palate, harelip, and webbed fingers/toes.
Prolonged use of Serophene may increase the risk of developing ovarian cancer.
Serophene may cause you to have blurred vision and see spots. These symptoms may cause problems when driving a car or operating machinery.
Also, Serophene may cause ovarian hyperstimulation syndrome (see "What side effects may occur?").
Serophene tablets should be taken only by mouth.
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Serophene.
Do not take Serophene if you are allergic to any of its ingredients. Also, do not use Serophene if you are pregnant, as it may cause harm to your unborn baby.
Avoid hazardous activities such as driving a car or operating heavy machinery, as Serophene may cause blurry vision.
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning therapy with Serophene. Also, talk to your doctor about your complete medical history.
Do not take Serophene if you are pregnant or breastfeeding. This drug may cause severe birth defects in your child, and may pass into your breast milk.
The usual dosage of Serophene begins low, at 50 milligrams daily (1 tablet) for 5 days. The dose should be increased to 100 milligrams for 5 days only in women who do not ovulate in response to the 50-milligram dose.
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.