Trade Names:Agoral- Liquid 25 mg
Trade Names:Black Draught- Granules 20 mg/5 mL- Tablets 6 mg
Trade Names:ex•lax- Tablets 15 mg
Trade Names:ex•lax chocolate- Tablets 15 mg
Trade Names:Fletcher Castoria- Liquid 33.3 mg/mL
Trade Names:Senexon- Tablets 8.5 mg
Trade Names:Senna-Gen- Tablets 8.6 mg
Trade Names:Senokot- Granules 15 mg/5 mL- Syrup 8.8 mg/5 mL- Tablets 8.6 mg
Trade Names:SenokotXTRA- Tablets 17 mgSenna Laxative Pills Extra Strength Peristaltic Stimulant (Canada)Senna Laxative Pills Regular Strength Peristaltic Stimulant (Canada)Senna Tablets Peristaltic Stimulant (Canada)
Directly acts on intestinal mucosa by altering water and electrolyte secretion, inducing peristalsis and defecation.
Short-term treatment of constipation; preoperative and preradiographic bowel evacuation for procedures involving GI tract.
Nausea, vomiting, or other symptoms of appendicitis; acute surgical abdomen; fecal impaction; intestinal obstruction; undiagnosed abdominal pain.
PO 2 tablets, 1 tsp of granules or 10 to 15 mL of syrup, usually at bedtime.
PR 1 suppository at bedtime; may repeat in 2 h.Children
Generally, for children 6 to 12 yr of age or more than 60 lb, give (at bedtime) 1 tablet or ½ tsp granules PO or ½ suppository PR . Liquid dose ranges from 1.25 to 15 mL depending on age and product formulation.
None well documented.
None well documented.
Excessive bowel activity (eg, griping, diarrhea, nausea, vomiting); perianal irritation; bloating; flatulence; abdominal cramping.
Assess bowel function, including normal frequency, type, last bowel movement, bowel sounds, abdominal distention.
Category C .
Long-term use may lead to laxative dependency, which may result in fluid and electrolyte imbalances, steatorrhea, osteomalacia, and vitamin and mineral deficiencies. Cathartic colon, a poorly functioning colon, results from long-term abuse. Pathologic presentation may resemble ulcerative colitis.
May result in yellow-brown urine.
May result in pink to red urine.
Excessive laxative use may lead to significant fluid and electrolyte imbalance.
Darkened pigmentation of colonic mucosa may occur after long-term use, usually resolving within 5 to 11 mo of discontinuation.
May indicate serious condition requiring further attention.
Gripping pain, diarrhea.
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