Generic Name: mazindol (MA zin doll)Brand Names: Mazanor, Sanorex
Mazindol is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an "anorectic" or an "anorexigenic" drug. Mazindol stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.
Mazindol is used as a short-term supplement to diet and exercise in the treatment of obesity.
Mazindol may also be used for purposes other than those listed in this medication guide.
have heart disease or high blood pressure;
have arteriosclerosis (hardening of the arteries);
have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; or
have a history of drug or alcohol abuse.
Before taking this medication, tell your doctor if you have
problems with your thyroid;
an anxiety disorder;
epilepsy or another seizure disorder; or
You may not be able to take mazindol, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.It is not known whether mazindol will harm an unborn baby. Do not take mazindol without first talking to your doctor if you are pregnant. It is also not known whether mazindol passes into breast milk. Do not take mazindol without first talking to your doctor if you are breast-feeding a baby.
Take mazindol exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.Take each dose with a full glass of water. Mazindol is usually taken one to three times a day before meals. Mazindol can be taken with food if it upsets your stomach. Follow your doctor's instructions. Never take more of this medication than is prescribed for you. Too much mazindol could be very dangerous to your health. Store mazindol at room temperature away from moisture and heat.
Symptoms of a mazindol overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.
an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
an irregular heartbeat or very high blood pressure (severe headache, blurred vision); or
hallucinations, abnormal behavior, or confusion.
Other, less serious side effects may be more likely to occur. Continue to take mazindol and talk to your doctor if you experience
restlessness or tremor,
nervousness or anxiety,
headache or dizziness,
dry mouth or an unpleasant taste in your mouth,
diarrhea or constipation, or
impotence or changes in your sex drive.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Changes in insulin and other diabetes drug therapies may be necessary during treatment with mazindol.
Mazindol may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine.
Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). These drugs may decrease the effects of mazindol.
Drugs other than those listed here may also interact with mazindol. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Mazindol is available with a prescription under the brand names Mazanor and Sanorex. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
Mazanor 1 mg--white, round, scored tablets
Sanorex 1 mg--white, round tablets
Sanorex 2 mg--white, round, scored tablets