Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index

Drugs A-Z List

Diseases & Conditions A-Z List

Herbs & Supplements

Medical Dictionary

Full Article

Popular Drugs

Popular Diseases & Conditions

Drugs reference index «Sanctura»



Generic name: Trospium chlorideBrand names: Sanctura

Why is Sanctura prescribed?

Sanctura is prescribed for the treatment of overactive bladder (OAB) in adults. People with overactive bladder experience a strong and urgent need to urinate (urgency), a need to urinate more often than normal (frequency), or uncontrolled urine leakage (incontinence).

In OAB, the muscle in the bladder wall spasms, causing a need to urinate even when the bladder is not full. It can also result in accidental urination. Sanctura blocks the signal that causes spasm, relaxing the muscle of the bladder wall and restoring more normal bladder function.

Most important fact about Sanctura

Sanctura can cause dizziness, drowsiness, and blurred vision. You must use caution when driving, operating machinery, or engaging in hazardous activities when taking Sanctura to prevent injury to yourself and others.

How should you take Sanctura?

Take Sanctura exactly as prescribed by your doctor, with a full glass of water, at least 1 hour before meals or on an empty stomach.

  • If you miss a dose...Take the forgotten dose 1 hour before your next meal, and then return to your regular schedule. Do not take two doses at once.
  • Storage instructions...Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Sanctura.

  • Side effects may include:Blurred vision, constipation, dizziness, drowsiness, dry eyes, dry mouth, headache, inability to urinate, gas, stomach upset/pain

Why should Sanctura not be prescribed?

You should not take Sanctura if:

  • You are unable to empty your bladder (urinary retention or urinary blockage).
  • You have delayed or slow emptying of your stomach (also called gastric retention).
  • You have uncontrolled narrow-angle glaucoma (high pressure inside the eye).

Special warnings about Sanctura

Sanctura should be used with caution if you have trouble emptying your bladder. Before taking Sanctura, make sure the doctor knows if you have liver or kidney disease, stomach or intestinal problems, severe constipation, ulcerative colitis, myasthenia gravis, or eye problems such as glaucoma. Sanctura may make these conditions worse.

Drink plenty of fluids and stay well hydrated during hot weather while taking Sanctura, since it can reduce your ability to sweat and contribute to the risk of heat exhaustion.

Sanctura can cause dry mouth. For temporary relief, try sucking on hard candy or chewing gum.

Sanctura has not been studied in children.

Possible food and drug interactions when taking Sanctura

Sanctura has not yet been shown to interact with other medicines. However, it may affect your body's ability to absorb other medicines and your doctor may make a dosage adjustment or closely monitor your condition if you are taking the following:


Certain other drugs may increase the effects of constipation, dry mouth, and drowsiness when taken with Sanctura, including medicines for anxiety, allergies, depression, muscle spasm, pain, and sleeplessness.

Avoid drinking alcohol with Sanctura, as it may increase the risk of side effects such as dizziness and drowsiness.

Meals that are high in fat can interfere with the absorption of Sanctura. Always take Sanctura at least 1 hour before meals or on an empty stomach.

Special information if you are pregnant or breastfeeding

The effects of taking Sanctura during pregnancy have not been studied. If you are pregnant or plan to become pregnant, contact your doctor immediately.

In clinical studies, Sanctura appeared in the breast milk of animals. It is not known whether Sanctura appears in human breast milk; talk to your doctor if you plan on breastfeeding.

Recommended dosage for Sanctura


The usual recommended dose of Sanctura is 20 mg once in the morning and once at night. Take it at least 1 hour before meals or on an empty stomach.

In cases of severe kidney disease, the recommended dose is 20 mg once at bedtime.

If you are 75 years or older, your doctor may decrease your dose or start you on a lower dose of 20 mg once a day.


Any medication taken in excess can have serious consequences. If you suspect an overdose, seek emergency treatment immediately.

  • Symptoms of overdose may include:Confusion; dry, hot, or flushed skin; enlarged pupils; extremely high blood pressure; fast heartbeat; hallucinations; inability to urinate; seizures; vomiting; and possibly coma
  • Sanctura Prescribing Information (FDA)
  • Sanctura Advanced Consumer (Micromedex) - Includes Dosage Information
  • Sanctura Consumer Overview
  • Sanctura MedFacts Consumer Leaflet (Wolters Kluwer)
  • Sanctura XR Prescribing Information (FDA)
  • Sanctura XR Extended-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

See Also...