Generic Name: pilocarpine (pie low CAR peen)Brand Names: Salagen
Pilocarpine is an agent that affects the nervous system. Pilocarpine increases saliva secretion in the mouth.
Pilocarpine is used in the treatment of dry mouth.
Pilocarpine may also be used for purposes other than those listed in this medication guide.What is the most important information I should know about Salagen (pilocarpine)?Pilocarpine may cause changes in vision, especially at night. Use caution when driving, operating machinery, or performing other hazardous activities. If you experience changes in vision, avoid these activities. Dehydration may be more likely to occur during treatment with pilocarpine, due to increased sweating. Use caution when exercising and when exposed to hot weather. Drink plenty of fluid to maintain adequate hydration.What should I discuss with my healthcare provider before taking Salagen (pilocarpine)?
Before taking pilocarpine, talk to your doctor if you have:
glaucoma or other eye problems
asthma, chronic bronchitis, emphysema, or other breathing or lung problems;
abnormal blood pressure or blood vessel problems;
You may not be able to take pilocarpine or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.Pilocarpine is in the FDA pregnancy category C. This means that it is not known whether pilocarpine will be harmful to an unborn baby. Do not take pilocarpine without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether pilocarpine passes into breast milk. Do not take pilocarpine without first talking to your doctor if you are breast-feeding a baby.
Take pilocarpine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.Take each dose with a full glass of water.
Pilocarpine can be taken with or without food.
It is important to take pilocarpine regularly to get the most benefit.Store pilocarpine at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of pilocarpine unless otherwise directed by your doctor.
Symptoms of a pilocarpine overdose may include headache, hallucinations, visual disturbances, sweating, chest pain, abnormal heart rate, abnormal blood pressure, vomiting, nausea, diarrhea, tremors, or confusion.
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
eye pain; or
confusion or changes in mental status or behavior.
Other, less serious side effects may also occur. Continue to take pilocarpine and talk to your doctor if you experience
changes in vision;
redness of the face and neck;
an increased urge to urinate.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Before taking pilocarpine, tell your doctor if you are taking any of the following medicines:
a heart or blood pressure medication;
a seizure medication;
a medication for Parkinson's disease or other medications for muscle control;
an antihistamine or allergy medications;
a medication for motion sickness;
an antidepressant or antipsychotic medication; or
a medication for stomach problems.
You may not be able to take pilocarpine, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.
Drugs other than those listed here also interact with pilocarpine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.