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Drugs reference index «ReoPro»



Generic Name: Abciximab (ab-SIKS-ih-mab)Brand Name: ReoPro

ReoPro is used for:

Preventing the formation of blood clots in the heart that may occur during procedures to open blocked arteries in the heart known as percutaneous coronary intervention (eg, balloon angioplasty, atherectomy, stent placement). It is also used in patients who have severe chest pain with heart disease (unstable angina) when percutaneous coronary intervention is planned. ReoPro is used in combination with other medicines.

ReoPro is an antithrombotic. It works by preventing the clumping of blood-clotting cells (called platelets) in the blood.

Do NOT use ReoPro if:

  • you are allergic to any ingredient in ReoPro or to specific disease-fighting protein substances called murine (mouse) monoclonal antibodies
  • you have had active internal bleeding; recent (within 6 weeks) gastrointestinal or genitourinary bleeding; trauma (within 2 years) to your head or spine; high blood pressure or problems with your blood, including bleeding easily or a stroke; low blood platelet count (known as thrombocytopenia); or recent (within 6 weeks) major surgery or trauma
  • you have had a growth or cancer of the brain or problems with blood vessels in the brain, blood vessel inflammation (vasculitis), or problems with your eyes, liver, or kidneys
  • you are or will be receiving dextran by injection
  • you are receiving or have received an anticoagulant (eg, warfarin) within the last 7 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using ReoPro :

Some medical conditions may interact with ReoPro . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have stomach ulcers or other stomach conditions
  • if you have clotting or blood disorders

Some MEDICINES MAY INTERACT with ReoPro . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin, heparin) within the last 7 days, dipyridamole, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), ticlopidine, or thrombolytics (t-PA) because the risk of bleeding may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if ReoPro may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use ReoPro :

Use ReoPro as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • ReoPro is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using ReoPro at home, carefully follow the injection procedures taught to you by your health care provider.
  • If ReoPro contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Keep this product, as well as syringes and needles, out of the reach of children. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of ReoPro , contact your doctor right away.

Ask your health care provider any questions you may have about how to use ReoPro .

Important safety information:

  • ReoPro may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to ReoPro . Using ReoPro alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • ReoPro may reduce the number of blood cells that are needed for clotting. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.
  • LAB TESTS, including blood counts and blood clotting tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • ReoPro is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using ReoPro during pregnancy. It is unknown if ReoPro is excreted in breast milk. Do not breast-feed while taking ReoPro .

Possible side effects of ReoPro :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; dizziness; general pain; headache; indigestion; nausea; pain at injection site; slow heart rate; stomach pain; swelling; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abdominal pain or swelling; black or bloody stools; chest pain; chills; continued redness or pain after an injection; coughing up blood; excessive or unusual bleeding; fever; increased menstrual bleeding; nosebleeds; pink or red urine; severe headache; slow heartbeat; vomiting blood or material that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of ReoPro :

Store ReoPro between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Do not shake. Discard any unused portion left in the vial. Keep ReoPro out of the reach of children and away from pets.

General information:

  • If you have any questions about ReoPro , please talk with your doctor, pharmacist, or other health care provider.
  • ReoPro is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about ReoPro . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • ReoPro Prescribing Information (FDA)
  • ReoPro Consumer Overview
  • Abciximab Professional Patient Advice (Wolters Kluwer)
  • Reopro Advanced Consumer (Micromedex) - Includes Dosage Information