Remodulin SolutionGeneric Name: Treprostinil
Remodulin Solution is used for:
Treating high blood pressure in the circulatory system of the lungs. It may also be used for other conditions as determined by your doctor.
Remodulin Solution is a prostaglandin. It works by relaxing blood vessels and increasing the supply of blood to the lungs in patients with high blood pressure in the lungs. This decreases how hard the heart must work to pump blood to the lungs.
Do NOT use Remodulin Solution if:
- you are allergic to any ingredient in Remodulin Solution
Contact your doctor or health care provider right away if any of these apply to you.
Before using Remodulin Solution:
Some medical conditions may interact with Remodulin Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, plan to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver or kidney problems, bleeding problems, swelling, or high sodium levels in the blood
Some MEDICINES MAY INTERACT with Remodulin Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide), vasodilators (eg, hydralazine), or blood pressure medicines (eg, lisinopril) because their actions and the risk of their side effects, such as low blood pressure, may be increased
- Blood thinners (eg, warfarin) because they may increase Remodulin Solution's actions and the risk of Remodulin Solution's side effects, including bleeding
This may not be a complete list of all interactions that may occur. Ask your health care provider if Remodulin Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Remodulin Solution:
Use Remodulin Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Remodulin Solution is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Remodulin Solution at home, a health care provider will teach you how to use it. Be sure you understand how to use Remodulin Solution. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Remodulin Solution is usually administered as an infusion by direct injection into the skin. It may be necessary for you to take Remodulin Solution for a prolonged period of time, possibly years. Additional treatment may require injecting medicine through the vein.
- Remodulin Solution is for injection beneath the skin or through the vein only.
- Do not use Remodulin Solution if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- If your dose is interrupted, contact your doctor or pharmacist immediately to establish a new dosing schedule.
Ask your health care provider any questions you may have about how to use Remodulin Solution.
Important safety information:
- Remodulin Solution may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Remodulin Solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Stopping Remodulin Solution, even briefly, may lead to serious side effects. To avoid interruption in medicine treatment you should have access to a backup infusion pump and infusion sets should your equipment fail.
- Depending on your condition, you may be given other medicines to help prevent blood clots. Take all prescribed medicines exactly as directed.
- Remodulin Solution may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
- Use Remodulin Solution with caution in the ELDERLY; they may be more sensitive to its effects.
- Remodulin Solution is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, contact your doctor. You will need to discuss the benefits and risks of using Remodulin Solution while you are pregnant. It is not known if Remodulin Solution is found in breast milk. If you are or will be breast-feeding while you are using Remodulin Solution, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Remodulin Solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; dizziness; flushing or redness of the skin; headache; jaw pain; joint or muscle aches; lightheadedness; nausea; pale skin; sweating; tiredness.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; changes in the appearance of the skin (eg, unusual paleness, blue/gray color); chest pain; dark, tarry stools; enlarged abdomen; fast, slow, or irregular heartbeat; fever; itching; mental or mood changes; pain, swelling, or redness at the injection site; shortness of breath; stomach pain; swelling of the legs; unexplained weight gain; unusual bruising or bleeding; unusual fatigue or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include fainting; nausea; severe dizziness; vomiting.Proper storage of Remodulin Solution:
Remodulin Solution is usually handled and stored by a health care provider. If you are using Remodulin Solution at home, store Remodulin Solution as directed by your pharmacist or health care provider. Keep Remodulin Solution out of the reach of children and away from pets.
- If you have any questions about Remodulin Solution, please talk with your doctor, pharmacist, or other health care provider.
- Remodulin Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Remodulin Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Remodulin Prescribing Information (FDA)
- Remodulin Advanced Consumer (Micromedex) - Includes Dosage Information
- Treprostinil Professional Patient Advice (Wolters Kluwer)
- treprostinil Inhalation Advanced Consumer (Micromedex) - Includes Dosage Information
- Tyvaso Prescribing Information (FDA)
- Tyvaso Consumer Overview