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Drugs and diseases reference index

Drugs reference index «Reclast»


Generic Name: Zoledronic Acid (ZOE-le-DRON-ik AS-id)Brand Name: Reclast

Reclast is used for:

Treating osteoporosis (weak bones) in women who are past menopause. It is used to help build bone in men with osteoporosis and to reduce the risk of bone fractures due to osteoporosis in certain patients. It is used to treat and prevent osteoporosis in certain patients treated with corticosteroids (eg, prednisone). It may also be used to treat Paget disease or other conditions as determined by your doctor.

Reclast is a bisphosphonate. It works by decreasing the breakdown of bone. This reduces the amount of calcium that is released into the blood from bones and helps to lower your blood calcium level.

Do NOT use Reclast if:

  • you are allergic to any ingredient in Reclast or to any other bisphosphonate (eg, alendronate)
  • you have severe kidney problems
  • you have low calcium levels
  • you are using another form of zoledronic acid

Contact your doctor or health care provider right away if any of these apply to you.

Before using Reclast :

Some medical conditions may interact with Reclast . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had asthma or other breathing problems from taking aspirin
  • if you have a history of kidney problems, low blood calcium levels, blood clotting problems, anemia, or bone infection
  • if you have a history of thyroid or parathyroid problems or if you have had thyroid or parathyroid surgery
  • if you have poor nutrition, nutrient absorption problems (eg, "malabsorption syndrome"), have had sections of your intestines removed; or are unable to take calcium or vitamin D supplements
  • if you have low blood volume, recent vomiting or diarrhea, decreased appetite, or if you are dehydrated
  • if you have cancer or are receiving radiation or chemotherapy
  • if you have dental problems or have planned dental surgery (eg, tooth extraction)

Some MEDICINES MAY INTERACT with Reclast . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Aminoglycoside antibiotics (eg, gentamicin) or diuretics (eg, furosemide) because the risk of low blood calcium levels may be increased
  • Corticosteroids (eg, prednisone) because the risk of jawbone problems may be increased
  • Medicines that may harm the kidney (eg, amphotericin B, cyclosporine, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg, ibuprofen], tacrolimus, vancomycin) or thalidomide because the risk of kidney problems may be increased. Ask your doctor if you are unsure if any of your medicines might harm the kidney

This may not be a complete list of all interactions that may occur. Ask your health care provider if Reclast may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Reclast :

Use Reclast as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Reclast . Talk to your pharmacist if you have questions about this information.
  • Reclast is usually given as an injection at your doctor's office, hospital, or clinic.
  • Drink at least 2 full glasses (16 oz/480 mL) of fluid (eg, water) within a few hours before you receive Reclast , as directed by your doctor.
  • If you miss a dose of Reclast , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Reclast .

Important safety information:

  • Reclast may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Reclast with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Follow the diet and exercise program given to you by your health care provider. Talk to your doctor about taking a calcium and vitamin D supplement while you use Reclast .
  • You may develop flu-like symptoms, mild fever, muscle or joint aches, or headache after you receive Reclast . If this occurs, a mild pain reliever (eg, acetaminophen, ibuprofen) may help to relieve these symptoms.
  • Reclast may cause jaw bone problems in some patients. Your risk may be greater if you have cancer, poor dental hygiene, or certain other conditions (eg, anemia, blood clotting problems, dental problems, infections). Your risk may also be greater if you use certain medicines or therapies (eg, chemotherapy, corticosteroids, radiation). Talk to your doctor about having a dental exam before you start to use Reclast . Ask your doctor any questions you may have about dental treatment while you use Reclast .
  • Proper dental care is important while you are taking Reclast . Brush and floss your teeth and visit the dentist regularly.
  • Certain dental procedures should be avoided if possible while you are using Reclast . Check with your doctor and dentist before having any dental treatments while using Reclast .
  • Lab tests, including kidney function, complete blood cell counts, and blood electrolyte levels (eg, calcium, magnesium, phosphate), may be performed while you use Reclast . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Reclast with caution in the ELDERLY, especially those with kidney problems; they may be more sensitive its effects.
  • Reclast should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use Reclast if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Reclast is found in breast milk. Do not breast-feed while you are using Reclast .

Possible side effects of Reclast :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; mild bone, joint, or muscle pain; mild flu-like symptoms (eg, mild fever, muscle aches); mild itching, pain, or redness at the injection site; nausea; stomach pain or upset; tiredness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); change in the amount of urine produced; eye pain, redness, or swelling; fever, chills, or persistent sore throat; irregular heartbeat; jaw pain or swelling; mental or mood changes (eg, depression); muscle cramps or spasms; numbness or tingling (especially around the mouth); severe bone, joint, or muscle pain; severe or persistent dizziness or headache; severe or persistent nausea, vomiting, or diarrhea; severe or persistent tiredness or weakness; shortness of breath; swelling of the hands, ankles, or feet.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include decreased urination; irregular heartbeat; mental or mood changes; muscle cramps; numbness or tingling (especially around the mouth).

Proper storage of Reclast :

Reclast is usually handled and stored by a health care provider. If you are using Reclast at home, store Reclast as directed by your pharmacist or health care provider. Keep Reclast out of the reach of children and away from pets.

General information:

  • If you have any questions about Reclast , please talk with your doctor, pharmacist, or other health care provider.
  • Reclast is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Reclast . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Reclast Prescribing Information (FDA)
  • Reclast Advanced Consumer (Micromedex) - Includes Dosage Information
  • Reclast Consumer Overview
  • Zoledronic Acid Professional Patient Advice (Wolters Kluwer)
  • Aclasta Consumer Overview
  • Zometa Prescribing Information (FDA)
  • Zometa Consumer Overview