Generic name: Prednisolone sodium phosphateBrand names: Orapred ODT
Orapred ODT is used to treat severe allergies that cannot be otherwise treated, in adults and children with asthma (or asthma caused by a different medical condition).
This drug is also used to treat skin diseases, kidney problems in people with lupus (such as proteinuria), stomach problems (such as ulcers), leukemia and lymphomas, multiple sclerosis, eye problems, rheumatologic issues (such as rheumatoid arthritis), tuberculosis, and meningitis.
While being treated with Orapred ODT, live vaccines should not be given, as Orapred ODT may suppress your immune system. Killed or inactivated vaccines can be administered, but the body's response cannot be predicted.
Orapred ODT tablets are packaged in a blister. You should not remove the tablet from the blister until you are ready to take it. The blister pack should then be peeled open, and the orally disintegrating tablet placed on the tongue, where it may be swallowed whole, or allowed to dissolve in the mouth, with or without water. Orapred ODT should not be cut, split, or broken.
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Orapred ODT.
Do not begin treatment with Orapred ODT if you are allergic to any of its ingredients, or if you have a fungal infection.
Avoid breaking Orapred ODT tablets, or taking pieces of tablets. Also, do not abruptly stop Orapred ODT; it should be withdrawn from gradually.
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Orapred ODT. Also, talk to your doctor about your complete medical history, especially if you have heart problems, kidney problems, stomach ulcers, a stomach infection, eye problems, or if you are going through menopause.
If Orapred ODT is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Orapred ODT with the following:
Amphotericin-BAspirin (or other non-steroidal anti-inflammatory agents)BarbituratesCyclosporinDiureticsEphedrineEstrogensKetoconazoleLive or inactivated vaccines.PhenytoinRifampinWarfarin
The effects of Orapred ODT during pregnancy and breastfeeding are unknown. Talk with your doctor before taking Orapred ODT if you are pregnant, plan to become pregnant, or are breastfeeding.
The initial dose of Orapred ODT ranges from 10 to 60 milligrams (mg) per day, depending on the specific disease being treated.
Multiple SclerosisThe usual daily doses are 200 mg of prednisolone for a week followed by 80 mg every other day, or 4 to 8 mg dexamethasone every other day for one.
The initial dose of Orapred may vary depending on the specific disease entity being treated. The range of initial doses is 0.14 to 2 mg/kg/day in three or four divided doses (4 to 60 mg/m2bsa/day).
Kidney ProblemsThe usual children's dosage is 60 mg/m2/day given in three divided doses for 4 weeks, followed by 4 weeks of single dose alternate-day therapy at 40 mg/m2/day.
Asthma Uncontrolled by an InhalerThe usual children's dosage is 1-2 mg/kg/day in single or divided doses.
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.