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Drugs reference index «Noxafil»


Generic name: PosaconazoleBrand names: Noxafil

Why is Noxafil prescribed?

Noxafil is used for treating fungal infections caused by Aspergillus or Candida. It is approved for use in people 13 years of age and older who are severely immunocompromised (for example, a fungal infection due to a side effect of chemotherapy).

Most important fact about Noxafil

If you are allergic to other antifungals, you should talk to your doctor before taking Noxafil.

People who have severe diarrhea or vomiting while being treated with Noxafil should be monitored closely for breakthrough fungal infections.

How should you take Noxafil?

Shake Noxafil well before taking it. Take each dose of Noxafil oral suspension with a full meal or liquid nutritional supplement. If you cannot eat a full meal or a nutritional supplement, a different type of antifungal therapy should be considered.

  • Storage instructions...Store at room temperature; do not freeze.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Noxafil.

  • Side effects may include:Breathing problems, constipation, cough, diarrhea, dizziness, fever, headache, loss of appetite, nausea, shakiness, stomach pain, tiredness, upset stomach, vomiting, weakness

Why should Noxafil not be prescribed?

Do not take Noxafil if you are allergic to any of its ingredients, or if you are taking any of the following drugs: ergot alkaloids, terfenadine, astemizole, cisapride, pimozide, halofantrine, or quinidine.

Special warnings about Noxafil

While taking Noxafil, avoid becoming pregnant or breastfeeding.

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Noxafil. Also, talk to your doctor about your complete medical history, especially if you have liver problems.

Possible food and drug interactions when taking Noxafil

If Noxafil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Noxafil with the following:

AstemizoleCalcium channel blockersCimetidineCisaprideErgot and vinca alkaloidsPhenytoinQuinidineRifabutinSirolimusStatinsTerfenadine

Special information if you are pregnant or breastfeeding

The effects of Noxafil during pregnancy and breastfeeding are unknown. Talk with your doctor before taking Noxafil if you are pregnant, plan to become pregnant, or are breastfeeding.

Recommended dosage for Noxafil


The usual dose is 200 milligrams taken three times a day.


Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

  • Noxafil Prescribing Information (FDA)
  • Noxafil Consumer Overview
  • Noxafil Advanced Consumer (Micromedex) - Includes Dosage Information
  • Noxafil Suspension MedFacts Consumer Leaflet (Wolters Kluwer)
  • Posaconazole Professional Patient Advice (Wolters Kluwer)