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Drugs reference index «Maxipime»

Maxipime

Generic Name: cefepime (Injection route)

SEF-e-peem

Commonly used brand name(s):

In the U.S.

  • Maxipime

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Antibiotic

Pharmacologic Class: 4th Generation Cephalosporin

Uses For Maxipime

Cefepime injection is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Before Using Maxipime

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of cefepime injection in children. However, safety and efficacy have not been established in children younger than 2 months of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefepime injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cefepime injection.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Brain disease (e.g., encephalopathy, severe confusion) or
  • Colitis (inflammation in gut), history of or
  • Diarrhea, severe, history of or
  • Myoclonus (muscle twitching or jerking) or
  • Seizures—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.

Proper Use of Maxipime

A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into one of your muscles or through a needle placed in one of your veins.

Precautions While Using Maxipime

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Cefepime injection may cause diarrhea, and in some cases it can be severe. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Check with your doctor right away if you or your child have any of the following symptoms while receiving this medicine: confusion; loss of consciousness; jerking or twitching of the muscles; seizures; seeing, hearing, or feeling things that are not there; or severe sleepiness.

Before you or your child have any medical tests, tell the medical doctor in charge that you are receiving this medicine. The results of some tests may be affected by this medicine.

Maxipime Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Abdominal or stomach cramps
  • back, leg, or stomach pains
  • bleeding gums
  • chills
  • confusion
  • convulsions
  • dark urine
  • difficulty with breathing
  • fever
  • general body swelling
  • headache
  • irregular heartbeats
  • loss of appetite
  • mood or mental changes
  • muscle cramps in the hands, arms, feet, legs, or face
  • nausea or vomiting
  • nosebleeds
  • numbness and tingling around the mouth, fingertips, or feet
  • pale skin
  • shortness of breath
  • sore throat
  • tremor
  • yellowing of the eyes or skin
Less common
  • Bluish color
  • changes in skin color
  • pain
  • swelling of the foot or leg
  • tenderness
Rare
  • Diarrhea
  • inflammation or swelling
  • watery or bloody diarrhea
Incidence not known
  • Agitation
  • back pain
  • blistering, peeling, or loosening of the skin
  • blood in the urine or stools
  • bloody or cloudy urine
  • bloody, black, or tarry stools
  • blurred vision
  • change in consciousness
  • chest pain
  • clay-colored stools
  • cloudy urine
  • coma
  • cough or hoarseness
  • coughing up blood
  • decrease in urine output or decrease in urine-concentrating ability
  • decreased awareness or responsiveness
  • difficult or painful urination
  • difficulty with swallowing
  • dizziness
  • drowsiness
  • fast heartbeat
  • fever with or without chills
  • general feeling of tiredness or weakness
  • high fever
  • hives
  • increased menstrual flow or vaginal bleeding
  • irritability
  • itching
  • joint or muscle pain
  • loss of appetite
  • loss of consciousness
  • lower back or side pain
  • muscle twitching or jerking
  • nosebleeds
  • painful or difficult urination
  • pale skin
  • paralysis
  • pinpoint red spots on the skin
  • prolonged bleeding from cuts
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red irritated eyes
  • red or black, tarry stools
  • red or dark brown urine
  • red skin lesions, often with a purple center
  • rhythmic movement of the muscles
  • seeing, hearing, or feeling things that are not there
  • seizures
  • severe sleepiness
  • shortness of breath
  • skin rash
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • stiff neck
  • sudden decrease in the amount of urine
  • swollen or painful glands
  • tightness in the chest
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting of blood
  • wheezing
  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Red streaks on the skin
  • swelling, tenderness, or pain at the injection site
Rare
  • Itching of the vagina or genital area
  • pain during sexual intercourse
  • redness of the skin
  • sore mouth or tongue
  • thick, white vaginal discharge with no odor or with a mild odor
  • white patches in the mouth, tongue, or throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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  • Maxipime MedFacts Consumer Leaflet (Wolters Kluwer)
  • Maxipime Concise Consumer Information (Cerner Multum)
  • Maxipime Prescribing Information (FDA)
  • Cefepime Professional Patient Advice (Wolters Kluwer)
  • Cefepime Prescribing Information (FDA)