Trade Names:Detussin- Liquid 5 mg hydrocodone bitartrate and 60 mg pseudoephedrine hydrochloride
Suppresses cough reflex; stimulates opiate receptors in the CNS and peripherally blocks pain impulse generation.Pseudoephedrine
Causes vasoconstriction and subsequent shrinkage of nasal mucous membranes by alpha-adrenergic stimulation, which promotes nasal drainage.
Suppression of cough and relief of nasal congestion and other symptoms associated with the common cold, allergies, hay fever, sinusitis, and other respiratory illnesses.
Hypersensitivity to any component of product, or hypersensitivity or idiosyncrasy to sympathomimetic amines which may be manifested by insomnia, dizziness, weakness, tremor, or arrhythmias. Patients known to be hypersensitive to other sympathomimetic amines may exhibit cross sensitivity with pseudoephedrine. Sympathomimetic amines are contraindicated in patients with severe hypertension, severe coronary artery disease, and patients on MAOI therapy. P-V-Tussin tablets are contraindicated in breast-feeding mothers because of the higher than usual risk for infants from sympathomimetic amines.
PO 1 tsp (5 mL) 4 times daily.
Measure and administer prescribed dose of liquid using dosing syringe, dosing spoon, or dosing cup.
Store elixir at controlled room temperature (59° to 86°F). Keep tightly capped.
Increased CNS depression (eg, drowsiness) may occur.
None well documented.
Cardiac arrhythmia; increased heart rate; increased BP.
Lightheadedness; dizziness; sedation; drowsiness; weakness; anxiety; fear; fatigue; dysphoria; psychological dependence; confusion.Pseudoephedrine
Convulsions; CNS stimulation; hallucinations; tremors.
Nausea; vomiting; constipation.
Decreased urination; urethral spasm.Pseudoephedrine
Dyspnea; respiratory depression; irregular breathing.Pseudoephedrine
Consult health care provider before use.
Consult health care provider before use.Hydrocodone
Excreted in breast milk.
As with any narcotic, P-V-Tussin tablets should be given with caution to certain patients such as the elderly or debilitated and those with severe impairment of hepatic or renal function, hypothyroidism, Addison disease, prostatic hypertrophy or urethral stricture, asthma, and narrow angle glaucoma.
Hydrocodone has abuse potential; may be habit forming.
Respiratory and CNS depression, circulatory collapse, cardiopulmonary arrest, deathPseudoephedrine
Cardiac arrhythmias, cerebral hemorrhage, pulmonary edema, palpitations, tremor, dizziness, vomiting, fear, labored breathing, headache, dryness of mouth, pallor, weakness, panic, anxiety, confusion, hallucination, delirium
Copyright © 2009 Wolters Kluwer Health.