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Drugs reference index «Histatrol»

Histatrol

Generic Name: histamine phosphate (Intradermal route)

HIS-ta-meen FOS-fate

Commonly used brand name(s):

In the U.S.

  • Histatrol

Available Dosage Forms:

  • Solution
  • Injectable

Therapeutic Class: Diagnostic Agent

Uses For Histatrol

Histamine is used to help diagnose problems or disease of the stomach. This test determines how much acid your stomach produces.

How the stomach test is done: Before this medicine is given, the stomach contents are emptied through a tube. Then the dose of histamine, which is based on body weight, is injected under the skin. Five minutes later, the stomach contents are emptied and tested for acidity. This procedure may be repeated several times. An antihistamine medicine may be given before the histamine is injected to prevent a possible unwanted effect.

Histamine is to be used only under the supervision of a doctor.

Before Using Histatrol

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, test results may be affected by other things. For histamine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing the use of histamine in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of histamine in the elderly with use in other age groups.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart disease—Histamine's effect on the heart may make the condition worse
  • High blood pressure (severe) or
  • Low blood pressure—Histamine may increase the high blood pressure further or lower an already low blood pressure
  • Kidney disease (severe)—The histamine may build up in the body and cause side effects
  • Lung disease (especially asthma)—There is a chance that this test may make the condition worse; for example, an asthma attack may occur
  • Pheochromocytoma—Histamine may cause serious damage to the brain and blood vessels.

Proper Use of Histatrol

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Precautions While Using Histatrol

Do not swallow saliva during the test. The saliva may affect the results of the test.

Histatrol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
  • Dizziness, lightheadedness, or fainting
  • fast or pounding heartbeat
  • headache (continuing or severe)
  • nervousness
Less common or rare
  • Convulsions (seizures)
  • difficulty in breathing
  • flushing or redness of face
With large doses
  • Bluish coloration of face
  • blurred vision
  • chest discomfort or pain
  • decrease in blood pressure (sudden)
  • diarrhea (severe)
  • difficulty in breathing (severe)
  • nausea and vomiting (severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abdominal or stomach spasms or cramps
  • diarrhea
  • metallic taste
  • nausea or vomiting
  • stomach pain
  • swelling or redness at place of injection

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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  • Histamine Phosphate Prescribing Information (FDA)